Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 16/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287330 | 0.90 | MEN1 (0.64) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287420 | 0.85 | TRPM8 (0.51) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287407 | 0.84 | TAS2R14 (0.81) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287314 | 0.78 | MEN1 (0.77) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287293 | 0.77 | MEN1 (0.60) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287531 | 0.77 | MEN1 (0.50) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287284 | 0.75 | MEN1 (0.73) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287426 | 0.74 | MEN1 (0.65) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1287316 | 0.74 | TAS2R14 (0.76) | TAS2R14KMT2AMEN1POLB | |
| SCHEMBL1169654 | 0.74 | TAS2R14 (1.00) | TAS2R14KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |