Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 6/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | GCG | P01275 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287468 | 0.86 | MEN1 (0.64) | MEN1KMT2APOLBCXCR3TMEM97 | |
| SCHEMBL1287330 | 0.86 | MEN1 (0.64) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287435 | 0.78 | MEN1 (0.66) | MEN1KMT2APOLBCXCR3TMEM97 | |
| SCHEMBL1287403 | 0.78 | MEN1 (0.62) | MEN1KMT2APOLBCXCR3TMEM97 | |
| SCHEMBL1287387 | 0.77 | TAS2R14 (0.57) | MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287293 | 0.75 | MEN1 (0.60) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL10461750 | 0.74 | MEN1 (0.75) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287336 | 0.74 | MEN1 (0.62) | MEN1KMT2APOLBCXCR3TMEM97 | |
| SCHEMBL1287415 | 0.73 | TP53 (0.61) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287273 | 0.73 | MEN1 (0.89) | MEN1KMT2APOLBCXCR3TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |