Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287453 | 0.84 | CXCR3 (0.72) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287601 | 0.84 | POLB (0.49) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287330 | 0.78 | MEN1 (0.64) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287273 | 0.78 | MEN1 (0.89) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287315 | 0.76 | MEN1 (0.70) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287293 | 0.76 | MEN1 (0.60) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL10461750 | 0.75 | MEN1 (0.75) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL13649481 | 0.74 | MEN1 (0.67) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287378 | 0.74 | MEN1 (0.73) | CXCR3MEN1KMT2APOLBTAS2R14 | |
| SCHEMBL1287284 | 0.74 | MEN1 (0.73) | CXCR3MEN1KMT2APOLBTAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |