SCHEMBL1287589

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29286594	0.89	EYA3 (0.70)	EYA3CYP2C19CYP2C9TTRMEN1
	SCHEMBL9195719	0.88	EYA3 (0.73)	EYA3CYP2C19CYP2C9TTRMEN1
	SCHEMBL9287304	0.86	EYA3 (0.53)	EYA3CYP2C19CYP2C9TTRMEN1
	SCHEMBL1287573	0.83	CYP2C19 (1.00)	EYA3CYP2C19CYP2C9TTRMEN1
	Benziodarone SCHEMBL31326233	0.83	EYA3 (1.00)	EYA3CYP2C19CYP2C9TTRMEN1
	Benziodarone SCHEMBL308541	0.83	EYA3 (1.00)	EYA3CYP2C19CYP2C9TTRMEN1
	Benzbromarone SCHEMBL48993	0.82	SLC22A12 (1.00)	EYA3CYP2C19CYP2C9TTRMEN1
	SCHEMBL1287534	0.82	CYP2C19 (0.74)	EYA3CYP2C19CYP2C9TTRMEN1
	Benzbromarone SCHEMBL19205474	0.82	SLC22A12 (1.00)	EYA3CYP2C19CYP2C9TTRMEN1
	Benzbromarone SCHEMBL29361528	0.82	SLC22A12 (1.00)	EYA3CYP2C19CYP2C9TTRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.