Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 8/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.53 |
| ▸ | TTR | P02766 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287589 | 0.86 | EYA3 (0.71) | EYA3CYP2C19CYP2C9TTRMEN1 | |
| SCHEMBL9195719 | 0.82 | EYA3 (0.73) | EYA3CYP2C19CYP2C9TTRMEN1 | |
| SCHEMBL9267705 | 0.80 | EYA3 (0.55) | EYA3CYP2C19CYP2C9TTRMEN1 | |
| SCHEMBL2141567 | 0.79 | EYA3 (0.69) | EYA3CYP2C19CYP2C9TTRMEN1 | |
| SCHEMBL11674647 | 0.76 | L3MBTL1 (0.52) | EYA3CYP2C19CYP2C9TTRMEN1 | |
| SCHEMBL4430343 | 0.76 | EYA3 (0.44) | EYA3CYP2C19CYP2C9TTRMEN1 | |
| SCHEMBL29286594 | 0.75 | EYA3 (0.70) | EYA3CYP2C19CYP2C9TTRMEN1 | |
| SCHEMBL10599107 | 0.75 | CYP2C19 (0.63) | EYA3CYP2C19CYP2C9MEN1KMT2A | |
| SCHEMBL10598815 | 0.74 | EYA3 (0.54) | EYA3CYP2C19CYP2C9SLC22A12PTPN1 | |
| SCHEMBL9605230 | 0.73 | EYA3 (0.43) | EYA3CYP2C19CYP2C9TTRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448850-B1 | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia | TARO PHARMA IND (IL) | 1995-08-30 | — | — | EP | disclosed |
| EP-0448850-A1 | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia | Taro Pharmaceutical Industries Ltd. (IL) | 1991-10-02 | — | — | EP | disclosed |
| EP-0448850-A1 | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia | Taro Pharmaceutical Industries Ltd. (IL) | 1991-10-02 | — | — | EP | disclosed |
| US-4975458-A | 2-alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia | TARO PHARMACEUTICALS INDUSTRIES, LTD. (IL) | 1990-12-04 | — | — | US | disclosed |
| US-4975458-A | 2-alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia | TARO PHARMACEUTICALS INDUSTRIES, LTD. (IL) | 1990-12-04 | — | — | US | disclosed |