Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144382 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAGFEREGFRPRKCI | |
| SCHEMBL14336221 | 0.84 | ALDH1A1 (0.46) | ALDH1A1GAAGFEREGFRKDM4E | |
| SCHEMBL2194027 | 0.83 | EGFR (0.56) | ALDH1A1EGFRPRKCIACHEHPGD | |
| SCHEMBL502012 | 0.83 | ALDH1A1 (0.45) | ALDH1A1GAAGFEREGFRKDM4E | |
| SCHEMBL13025363 | 0.83 | ALDH1A1 (0.45) | ALDH1A1GAAGFEREGFRPRKCI | |
| SCHEMBL3545527 | 0.82 | EGFR (0.75) | ALDH1A1GAAGFEREGFRKDM4E | |
| SCHEMBL30605142 | 0.82 | EGFR (0.75) | ALDH1A1GAAGFEREGFRKDM4E | |
| SCHEMBL23713473 | 0.81 | GAA (0.44) | ALDH1A1GAAGFEREGFRKDM4E | |
| SCHEMBL9159002 | 0.81 | HSD17B10 (0.49) | ALDH1A1GAAGFERKDM4EHSD17B10 | |
| SCHEMBL8145260 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GAAGFEREGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028757-A1 | MANUFACTURING METHOD OF 2-HYDROXY-5-PHENYLALKYLAMINOBENZOIC ACID DERIVATIVES AND THEIR SALTS | NEUROTECH PHARMACEUTICALS CO., LTD. (KR) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028757-A1 | MANUFACTURING METHOD OF 2-HYDROXY-5-PHENYLALKYLAMINOBENZOIC ACID DERIVATIVES AND THEIR SALTS | PAH, HACL2, HAAO | ALDH1A1 117/4885GAA 367/4885GFER 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.