Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1624350 | 0.87 | GAA (0.61) | ALDH1A1GAAMAPTHTTTSHR | |
| SCHEMBL2190989 | 0.86 | DPP4 (0.49) | HSD17B10ALDH1A1GAAMAPTHTT | |
| SCHEMBL2561432 | 0.85 | HSD17B10 (0.46) | HSD17B10ALDH1A1GAAMAPTHTT | |
| SCHEMBL28142858 | 0.85 | HSD17B10 (0.50) | HSD17B10ALDH1A1GAAMAPTHTT | |
| SCHEMBL8144382 | 0.84 | ALDH1A1 (0.47) | HSD17B10ALDH1A1GAAMAPTHTT | |
| SCHEMBL8550870 | 0.84 | ADRA1A (0.45) | ALDH1A1GAAMAPTHTTTSHR | |
| SCHEMBL4405092 | 0.84 | HSD17B10 (0.46) | HSD17B10ALDH1A1GAAMAPTHTT | |
| SCHEMBL14336221 | 0.83 | ALDH1A1 (0.46) | HSD17B10ALDH1A1GAAMAPTHTT | |
| SCHEMBL2560656 | 0.82 | KDM4E (0.49) | HSD17B10ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL13025363 | 0.81 | ALDH1A1 (0.45) | HSD17B10ALDH1A1GAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |