Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990328 | 0.89 | ALDH1A1 (0.39) | ALDH1A1GAAGFERHSP90AB1MAPT | |
| SCHEMBL8144382 | 0.87 | ALDH1A1 (0.47) | ALDH1A1GAAGFERHSP90AB1MAPT | |
| SCHEMBL502012 | 0.84 | ALDH1A1 (0.45) | ALDH1A1GAAGFERHSP90AB1MAPT | |
| SCHEMBL13025363 | 0.84 | ALDH1A1 (0.45) | ALDH1A1GAAGFERHSP90AB1MAPT | |
| SCHEMBL12877592 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GAAGFERHSP90AB1MAPT | |
| SCHEMBL10272847 | 0.84 | CYP17A1 (0.41) | ALDH1A1GAAKDM4EGLA | |
| SCHEMBL23713473 | 0.83 | GAA (0.44) | ALDH1A1GAAGFERHSP90AB1MAPT | |
| SCHEMBL9159002 | 0.83 | HSD17B10 (0.49) | ALDH1A1GAAGFERMAPTTNF | |
| SCHEMBL2129842 | 0.82 | ALDH1A1 (0.50) | ALDH1A1GAAGFERHSP90AB1MAPT | |
| SCHEMBL4090632 | 0.81 | GAA (0.58) | ALDH1A1GAAGFERHSP90AB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146209-A2 | PHOTOPOLYMERIZABLE COMPOSITIONS | DENTSPLY INTERNATIONAL INC. (US) | 2007-12-21 | — | — | WO | disclosed |