SCHEMBL1287844

SCHEMBL1287844

C1CCCCCNCCCCC1.[Gd]

nearest known ligand 0.90

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.90
CXCR4 P61073 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HIF1A Q16665 1/20 0.46
MAPT P10636 1/20 0.46
PDE4A P27815 1/20 0.46
KDR P35968 1/20 0.46
CA2 P00918 1/20 0.30
CHKA P35790 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3071895 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL3498160 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL3069642 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL8253733 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL11283826 0.95
SCHEMBL11508384 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL8435190 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL21753221 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL21819962 0.95 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Azepane SCHEMBL11361504 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1861043-B1 DEVICE AND SYSTEM FOR AIDING VALVE ANNULOPLASTY MEDTRONIC VASCULAR INC (US) 2019-08-07 EP claimed
US-9101669-B2 Self-assembed conjugate and use thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-08-11 US claimed
US-20130195751-A1 SELF-ASSEMBED CONJUGATE AND USE THEREOF POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-08-01 US claimed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 US claimed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 EP claimed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 WO claimed
US-7955385-B2 Device, system, and method for aiding valve annuloplasty MEDTRONIC VASCULAR, INC. (US) 2011-06-07 US claimed
EP-1861043-A1 DEVICE, SYSTEM, AND METHOD FOR AIDING VALVE ANNULOPLASTY Medtronic Vascular, Inc. (US) 2007-12-05 EP claimed
US-20070238979-A1 Reference Devices for Placement in Heart Structures for Visualization During Heart Valve Procedures MEDTRONIC VASCULAR, INC. (US) 2007-10-11 US claimed
WO-2006093656-A1 DEVICE, SYSTEM, AND METHOD FOR AIDING VALVE ANNULOPLASTY MEDTRONIC VASCULAR, INC. (US) 2006-09-08 WO claimed
US-20060195134-A1 Device, system, and method for aiding valve annuloplasty MEDTRONIC VASCULAR, INC. (US) 2006-08-31 US claimed
EP-3998336-B1 MICROORGANISMS AND METHODS FOR PRODUCING CANNABINOIDS AND CANNABINOID DERIVATIVES UNIV CALIFORNIA (US) 2026-01-07 EP disclosed
US-12460185-B2 Optimized cannabinoid synthase polypeptides DEMETRIX, INC. (US) 2025-11-04 US disclosed
US-12215327-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-04 US disclosed
US-12048710-B2 Compositions and methods for modification of biomolecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-30 US disclosed
EP-1812031-A2 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-08-01 EP disclosed
WO-2006093656-A1 DEVICE, SYSTEM, AND METHOD FOR AIDING VALVE ANNULOPLASTY MEDTRONIC VASCULAR, INC. (US) 2006-09-08 WO disclosed
US-20060195134-A1 Device, system, and method for aiding valve annuloplasty MEDTRONIC VASCULAR, INC. (US) 2006-08-31 US disclosed
US-20060110782-A1 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-25 US disclosed
WO-2006050262-A2 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12048710-B2 Compositions and methods for modification of biomolecules PTMS, QPCT, ANPEP ALDH1A1 3718/4885CXCR4 562/4885SMN1; SMN2 4689/4885
US-12215327-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives CNR2, CNR1, FAAH ALDH1A1 2306/4885CXCR4 1430/4885SMN1; SMN2 4846/4885
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES UACA, PAM, JAK3 ALDH1A1 1369/4885CXCR4 1841/4885SMN1; SMN2 4637/4885
US-20060110782-A1 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling PTMS, QPCT, DNPEP ALDH1A1 3269/4885CXCR4 1258/4885SMN1; SMN2 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.