Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.51 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414835 | 0.86 | ALDH1A1 (0.52) | EPHX2ALDH1A1MEN1KMT2AKCNQ2 | |
| SCHEMBL4414837 | 0.86 | ALDH1A1 (0.52) | EPHX2ALDH1A1MEN1KMT2AKCNQ2 | |
| SCHEMBL27531840 | 0.85 | MEN1 (0.50) | EPHX2ALDH1A1MEN1KMT2AKCNQ2 | |
| SCHEMBL24710028 | 0.83 | MAPK1 (0.63) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL29179535 | 0.83 | MAPK1 (0.63) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL30852958 | 0.83 | MAPK1 (0.63) | ALDH1A1MEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL15065815 | 0.82 | NLRP3 (0.50) | ALDH1A1HPGDCTBP2SIGMAR1CNR2 | |
| SCHEMBL6709399 | 0.82 | MEN1 (0.51) | EPHX2ALDH1A1MEN1KMT2AKCNQ2 | |
| SCHEMBL5322005 | 0.82 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AKCNQ2HPGD | |
| SCHEMBL6386462 | 0.81 | MEN1 (0.59) | EPHX2ALDH1A1MEN1KMT2AKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028509-A1 | Sulfonamides | MERCK SERONO SA (CH) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028509-A1 | Sulfonamides | CXCR3, CXCR2, CXCR1 | EPHX2 791/4885ALDH1A1 716/4885MEN1 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.