Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009982 | 0.91 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPTDRD1CYP3A4 | |
| SCHEMBL12446368 | 0.84 | CYP3A4 (0.42) | ALDH1A1MAPTDRD1CYP3A4TDP1 | |
| SCHEMBL29597288 | 0.84 | CYP3A4 (0.42) | ALDH1A1MAPTDRD1CYP3A4TDP1 | |
| SCHEMBL17426096 | 0.83 | CYP3A4 (0.38) | DRD1CYP3A4TDP1 | |
| SCHEMBL31566348 | 0.77 | HSD11B1 (0.30) | — | |
| SCHEMBL1043812 | 0.77 | HSD11B1 (0.30) | — | |
| SCHEMBL13177945 | 0.76 | CYP3A4 (0.34) | DRD1CYP3A4TDP1 | |
| SCHEMBL7024931 | 0.76 | ESR1 (0.36) | ALDH1A1MAPTDRD1CYP3A4TDP1 | |
| SCHEMBL4205832 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRDRD1CYP3A4TDP1 | |
| SCHEMBL3115547 | 0.72 | DPP4 (0.41) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186725-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC REDUCTIVE AMINATION OF CARBONYL COMPOUNDS | BASF SE (DE) | 2018-07-05 | — | — | US | disclosed |
| US-9975837-B2 | Method for synthesizing optically active carbonyl compounds | BASF SE (DE) | 2018-05-22 | — | — | US | disclosed |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | BASF SE (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-22 | — | — | US | disclosed |
| US-8623621-B2 | Method for producing optically active 2-methyl-alkanols | BASF SE (DE) | 2014-01-07 | — | — | US | disclosed |
| US-20110045560-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2-METHYL-ALKANOLS | BASF AKTIENGESELLSCHAFT (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | POF1B, FGFR1, COASY | ALDH1A1 861/4885TSHR 2334/4885MAPT 4198/4885 |
| US-20180186725-A1 | METHOD FOR THE HOMOGENEOUS CATALYTIC REDUCTIVE AMINATION OF CARBONYL COMPOUNDS | CAT, AOC1, CYCS | ALDH1A1 553/4885TSHR 3414/4885MAPT 3635/4885 |
| US-20180057437-A1 | METHOD FOR SYNTHESIZING OPTICALLY ACTIVE CARBONYL COMPOUNDS | CBR3, CBR1, HRH4 | ALDH1A1 653/4885TSHR 188/4885MAPT 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.