Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28933863 | 0.76 | TSHR (0.52) | TP53TSHRMAP2K4BCL2L1BAD | |
| SCHEMBL19403602 | 0.72 | ALDH1A1 (0.42) | TP53KDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL14018385 | 0.70 | TSHR (0.80) | TP53TSHRBCL2L1BADALDH1A1 | |
| SCHEMBL69873 | 0.70 | TSHR (0.80) | TP53TSHRBCL2L1BADALDH1A1 | |
| SCHEMBL2637326 | 0.70 | TSHR (0.80) | TP53TSHRBCL2L1BADALDH1A1 | |
| Terephthalic Acid SCHEMBL9577834 | 0.70 | TSHR (0.80) | TP53TSHRBCL2L1BADALDH1A1 | |
| Terephthalic Acid SCHEMBL1006723 | 0.69 | TSHR (0.92) | TP53TSHRBCL2L1BADALDH1A1 | |
| Terephthalic Acid SCHEMBL9484769 | 0.69 | TSHR (0.92) | TP53TSHRBCL2L1BADALDH1A1 | |
| SCHEMBL12987957 | 0.67 | TSHR (0.75) | TP53TSHRBCL2L1BADALDH1A1 | |
| Water SCHEMBL22788424 | 0.67 | TSHR (0.75) | TP53TSHRBCL2L1BADALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |