Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.69 |
| ▸ | DAO | P14920 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9484769 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1010632 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL996091 | 0.92 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117983015-A | Carbon dioxide adsorbing material | 重庆大学 | 2024-05-07 | — | — | CN | claimed |
| CN-111392751-B | Method for preparing ultra-dispersed nano magnesium oxide for chlorinated polyethylene by using alkali decrement wastewater | 常州市五洲环保科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-114479340-A | Composite plastic modified material | 常州市五洲环保科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113150462-A | Preparation method of composite PVC processing modification additive | 广东鑫达新材料科技有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-112898714-A | Preparation and application of multifunctional efficient PVC modified processing aid | 广东鑫达新材料科技有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-112500536-A | Preparation method of long-acting anti-tarnishing anti-aging agent | 常州市五洲化工有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-111392751-A | Method for preparing ultra-dispersed nano magnesium oxide for chlorinated polyethylene by using alkali decrement wastewater | 常州市五洲环保科技有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-110922728-A | Organic nucleating agent for preparing heat-resistant polylactic resin and preparation method thereof | 蚌埠学院 | 2020-03-27 | — | — | CN | claimed |
| CN-110684246-A | Tread rubber of low-saturation pattern oil-resistant tire and preparation method thereof | 徐州徐轮橡胶有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-104086803-B | A kind of rubber anti-ageing agent | CHANGZHOU WUZHOU CHEMICAL CO., LTD. (CN) | 2016-06-01 | — | — | CN | claimed |
| EP-2163232-A1 | Cement for sealer | GC Corporation (JP) | 2010-03-17 | — | — | EP | claimed |
| EP-1158592-B1 | Solid or gel electrolyte and battery using the same | SONY CORP (JP) | 2005-09-07 | — | — | EP | claimed |
| US-6764612-B2 | Encapsulated peroxide compositions | GEO SPECIALTY CHEMICALS, INC. | 2004-07-20 | — | — | US | claimed |
| US-6699622-B2 | CONTAINING POLYMERIZABLE ACIDITY MONOMER | SONY CORPORATION (JP) | 2004-03-02 | — | — | US | claimed |
| US-6699403-B2 | ORGANIC PEROXIDE ENTRAINED IN PRECIPITATED METALLIC SOAP | GEO SPECIALTY CHEMICALS, INC. | 2004-03-02 | — | — | US | claimed |
| WO-2003082734-A1 | SUPPORTED PEROXIDE COMPOSITIONS | GEO SPECIALTY CHEMICALS, INC. (US) | 2003-10-09 | — | — | WO | claimed |
| US-20030178600-A1 | Encapsulated peroxide compositions | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
| US-20030178599-A1 | Supported peroxides | GEO SPECIALTY CHEMICALS, INC. | 2003-09-25 | — | — | US | claimed |
| US-20020031710-A1 | Containing polymerizable acidity monomer | SONY CORPORATION (JP) | 2002-03-14 | — | — | US | claimed |
| EP-1158592-A2 | Solid or gel electrolyte and battery using the same | SONY CORPORATION (JP) | 2001-11-28 | — | — | EP | claimed |