Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331127 | 0.89 | GABRA1 (0.54) | CTNNB1GABRA1GABRB2TDP1ACP3 | |
| Sulfuric Acid SCHEMBL1282450 | 0.88 | CTNNB1 (0.46) | CTNNB1GABRA1GABRB2NQO2TDP1 | |
| SCHEMBL10456006 | 0.87 | GABRA1 (0.52) | CTNNB1GABRA1GABRB2TDP1ACP3 | |
| SCHEMBL10456008 | 0.87 | GABRA1 (0.52) | CTNNB1GABRA1GABRB2TDP1ACP3 | |
| Sulfuric Acid SCHEMBL11504691 | 0.82 | SLC2A1 (0.44) | GABRA1GABRB2TDP1CYP1A2CYP2C19 | |
| Sulfuric Acid SCHEMBL28463159 | 0.81 | SLC2A1 (0.43) | GABRA1GABRB2TDP1CYP1A2CYP2C19 | |
| Sulfuric Acid SCHEMBL6655702 | 0.80 | TDP1 (0.55) | NQO2TDP1CA2ACP3CYP1A2 | |
| Sulfuric Acid SCHEMBL7622004 | 0.80 | TDP1 (0.55) | NQO2TDP1CA2ACP3CYP1A2 | |
| SCHEMBL634474 | 0.79 | CYP2D6 (0.40) | GABRA1GABRB2TDP1CYP2D6 | |
| SCHEMBL10630320 | 0.79 | HPRT1 (0.52) | CTNNB1GABRA1GABRB2TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2741921-A1 | TRANSPARENT INK-JET RECORDING FILMS | Carestream Health, Inc. (US) | 2014-06-18 | — | — | EP | disclosed |
| EP-2648921-A1 | TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS | Carestream Health, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-2629981-A1 | TRANSPARENT INK- JET RECORDING FILMS | Carestream Health, Inc. (US) | 2013-08-28 | — | — | EP | disclosed |
| EP-2625042-A1 | TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS | Carestream Health, Inc. (US) | 2013-08-14 | — | — | EP | disclosed |
| WO-2013025383-A1 | TRANSPARENT INK-JET RECORDING FILMS | CARESTREAM HEALTH, INC. (US) | 2013-02-21 | — | — | WO | disclosed |
| WO-2012166403-A1 | TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS | CARESTREAM HEALTH, INC. (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012078483-A1 | TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS | CARESTREAM HEALTH, INC. (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012065011-A1 | TRANSPARENT INK-JET RECORDING FILMS COMPOSITIONS, AND METHODS | CARESTREAM HEALTH, INC. (US) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012054371-A1 | TRANSPARENT INK- JET RECORDING FILMS | CARESTREAM HEALTH, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012047943-A1 | TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS | CARESTREAM HEALTH, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012047822-A1 | TRANSPARENT INK-JET RECORDING FILMS, COMPOSITIONS, AND METHODS | CARESTREAM HEALTH, INC. (US) | 2012-04-12 | — | — | WO | disclosed |