Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7622004 | 1.00 | TDP1 (0.55) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL599659 | 0.87 | CYP2C19 (0.62) | TDP1ACP3CYP2C19CYP3A4CTRC | |
| SCHEMBL29490353 | 0.87 | CYP2C19 (0.62) | TDP1ACP3CYP2C19CYP3A4CTRC | |
| Sulfuric Acid SCHEMBL11511244 | 0.86 | CA2 (0.51) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| Sulfuric Acid SCHEMBL27445633 | 0.86 | CA2 (0.51) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL15851418 | 0.86 | TTR (0.50) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL13718279 | 0.84 | CYP2C19 (0.47) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL9142087 | 0.84 | CTRC (0.47) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL659516 | 0.84 | CYP2C19 (0.60) | TDP1ACP3CYP2C19CYP3A4CTRC | |
| Hydrogen Sulfide SCHEMBL11348128 | 0.84 | CYP2C19 (0.60) | TDP1ACP3CYP2C19CYP3A4CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111378381-A | Chemical mechanical polishing solution | 安集微电子（上海）有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-111378381-A | Chemical mechanical polishing solution | 安集微电子（上海）有限公司 | 2020-07-07 | — | — | CN | disclosed |
| EP-0959123-B1 | Water soluble granulate of phthalocyanine compounds | CIBA SC HOLDING AG (CH) | 2004-07-28 | — | — | EP | disclosed |
| EP-0959123-A1 | Water soluble granulate of phthalocyanine compounds | Ciba SC Holding AG (CH) | 1999-11-24 | — | — | EP | disclosed |