Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6655702 | 1.00 | TDP1 (0.55) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL599659 | 0.87 | CYP2C19 (0.62) | TDP1ACP3CYP2C19CYP3A4CTRC | |
| SCHEMBL29490353 | 0.87 | CYP2C19 (0.62) | TDP1ACP3CYP2C19CYP3A4CTRC | |
| Sulfuric Acid SCHEMBL11511244 | 0.86 | CA2 (0.51) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| Sulfuric Acid SCHEMBL27445633 | 0.86 | CA2 (0.51) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL15851418 | 0.86 | TTR (0.50) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL13718279 | 0.84 | CYP2C19 (0.47) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL9142087 | 0.84 | CTRC (0.47) | TDP1ACP3CA2CYP2C19CYP3A4 | |
| SCHEMBL659516 | 0.84 | CYP2C19 (0.60) | TDP1ACP3CYP2C19CYP3A4CTRC | |
| Hydrogen Sulfide SCHEMBL11348128 | 0.84 | CYP2C19 (0.60) | TDP1ACP3CYP2C19CYP3A4CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123300-B1 | PHOSPHORIC ACID ESTERS | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-1123300-A1 | PHOSPHORIC ACID ESTERS | Bayer Aktiengesellschaft (DE) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024749-A1 | PHOSPHORIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-04 | — | — | WO | disclosed |
| EP-0648816-B1 | Dyeing of leather with dyestuff mixtures | CIBA SC HOLDING AG (CH) | 2000-01-26 | — | — | EP | disclosed |
| EP-0558450-B1 | Process for dyeing leather with mixtures of dyes | CIBA GEIGY AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| EP-0648816-A1 | Dyeing of leather with dyestuff mixtures | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| EP-0558450-A1 | Process for dyeing leather with mixtures of dyes | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |
| EP-0224845-B1 | WATER-DISPERSIBLE GRANULES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0224845-A1 | Water-dispersible granules | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-10 | — | — | EP | disclosed |