Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149899 | 0.90 | LMNA (0.59) | ALDH1A1LMNASMN1; SMN2CTSLCTSB | |
| SCHEMBL24297219 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL1289902 | 0.84 | MCHR1 (0.44) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL31550489 | 0.84 | LMNA (0.51) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL31550495 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL30440860 | 0.82 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL8178335 | 0.82 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL5873775 | 0.82 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL8149664 | 0.82 | PRSS1 (0.73) | ALDH1A1LMNASMN1; SMN2PRSS1TPSAB1 | |
| SCHEMBL15795370 | 0.81 | LMNA (0.50) | ALDH1A1LMNASMN1; SMN2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150575-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E. I. du Pont de Nemours and Company (US) | 2017-04-05 | — | — | EP | claimed |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-10 | — | — | US | claimed |
| EP-2621894-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | claimed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | claimed |
| US-20230303482-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY | 2023-09-28 | — | — | US | disclosed |
| US-20230303482-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY | 2023-09-28 | — | — | US | disclosed |
| US-20230303482-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY | 2023-09-28 | — | — | US | disclosed |
| EP-3150575-B1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | DU PONT (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3150575-B1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | DU PONT (US) | 2023-08-09 | — | — | EP | disclosed |
| US-11613516-B2 | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2023-03-28 | — | — | US | disclosed |
| US-11613516-B2 | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2023-03-28 | — | — | US | disclosed |
| US-10745344-B2 | Method for preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-10 | — | — | US | disclosed |
| JP-2013537914-A | — | — | 2013-10-07 | — | — | JP | disclosed |
| EP-2621894-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| EP-2621894-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| CN-103124721-A | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | DU PONT | 2013-05-29 | — | — | CN | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303482-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | NAAA, SAT1, NAA15 | ALDH1A1 296/4885LMNA 1566/4885SMN1; SMN2 511/4885 |
| US-11613516-B2 | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | NAAA, SAT1, NAA15 | ALDH1A1 277/4885LMNA 1635/4885SMN1; SMN2 433/4885 |
| US-10745344-B2 | Method for preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide | NAAA, SAT1, NAA15 | ALDH1A1 277/4885LMNA 1635/4885SMN1; SMN2 433/4885 |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | NAAA, SAT1, NAA15 | ALDH1A1 277/4885LMNA 1635/4885SMN1; SMN2 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.