Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289835 | 0.84 | ALDH1A1 (0.55) | MCHR1ALDH1A1MAPK1KDM1ARCOR1 | |
| SCHEMBL1710151 | 0.82 | POLB (0.49) | ALDH1A1MAPK1POLBKDM1ARCOR1 | |
| SCHEMBL8149899 | 0.78 | LMNA (0.59) | ALDH1A1POLBCTSLCTSBCTSS | |
| SCHEMBL7466451 | 0.74 | HTT (0.61) | POLBLMNASMN1; SMN2TPSAB1TPSD1 | |
| SCHEMBL24297219 | 0.72 | ALDH1A1 (0.55) | MCHR1ALDH1A1MAPK1KDM1ARCOR1 | |
| SCHEMBL31550489 | 0.71 | LMNA (0.51) | ALDH1A1MAPK1KDM1ARCOR1FUCA1 | |
| SCHEMBL432657 | 0.71 | KMT2A (0.49) | ALDH1A1MAPK1POLBLMNASMN1; SMN2 | |
| SCHEMBL19031286 | 0.70 | SMN1; SMN2 (0.50) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL31550495 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MAPK1KDM1ARCOR1FUCA1 | |
| SCHEMBL30980576 | 0.70 | LMNA (0.64) | POLBLMNASMN1; SMN2HRH4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621894-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |