Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485775 | 0.83 | GAA (0.63) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936614 | 0.81 | GAA (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936673 | 0.81 | ALDH1A1 (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL1663526 | 0.79 | NAPRT (0.60) | GAAKDM4EMAPTPLK1NAPRT | |
| SCHEMBL9935825 | 0.78 | GAA (0.57) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936655 | 0.77 | KDM4E (0.61) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL21812523 | 0.77 | GAA (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL21812521 | 0.77 | GAA (0.56) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9937087 | 0.77 | KMT2A (0.59) | GAAKDM4EMAPTALDH1A1HTT | |
| SCHEMBL9936906 | 0.77 | GAA (0.51) | GAAKDM4EMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12521333-B2 | Composition comprising compound of thiopyridinone type and polyglyceryl-based emulsifiers | L'OREAL (FR) | 2026-01-13 | — | — | US | claimed |
| US-20250381115-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | claimed |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | claimed |
| US-20250375367-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-11 | — | — | US | claimed |
| US-20250367096-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-04 | — | — | US | claimed |
| US-20250205131-A1 | COSMETIC COMPOSITION COMPRISING THIOPYRIDINONE COMPOUNDS, REDUCING AGENT AND ARGININE | L'OREAL (FR) | 2025-06-26 | — | — | US | claimed |
| US-12226506-B2 | Cosmetic composition comprising natural emulsifiers and thiopyridinone compounds | L'OREAL (FR) | 2025-02-18 | — | — | US | claimed |
| US-20230404879-A1 | ENHANCING PHOTOSTABILITY OF THIOPYRIDINONE COMPOUND WITHOUT THE USE OF UV FILTERS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| US-20230404883-A1 | COSMETIC COMPOSITION COMPRISING NATURAL EMULSIFIERS AND THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| US-20230404884-A1 | COSMETIC COMPOSITION COMPRISING HYDROPHILIC ANTIOXIDANTS AND THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| US-20230404882-A1 | COMPOSITION COMPRISING COMPOUND OF THIOPYRIDINONE TYPE AND POLYGLYCERYL-BASED EMULSIFIERS | L'OREAL (FR) | 2023-12-21 | — | — | US | claimed |
| EP-2651897-B1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | OREAL (FR) | 2020-04-01 | — | — | EP | claimed |
| EP-2651897-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'Oréal (FR) | 2013-10-23 | — | — | EP | claimed |
| WO-2012080075-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2012-06-21 | — | — | WO | claimed |
| US-12521333-B2 | Composition comprising compound of thiopyridinone type and polyglyceryl-based emulsifiers | L'OREAL (FR) | 2026-01-13 | — | — | US | disclosed |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-20250381115-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | OREAL (FR) | 2025-12-18 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| WO-2012080075-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230404882-A1 | COMPOSITION COMPRISING COMPOUND OF THIOPYRIDINONE TYPE AND POLYGLYCERYL-BASED EMULSIFIERS | PPARG, PHOSPHO1, SQLE | GAA 1405/4885KDM4E 1549/4885MAPT 2629/4885 |
| US-20230404884-A1 | COSMETIC COMPOSITION COMPRISING HYDROPHILIC ANTIOXIDANTS AND THIOPYRIDINONE COMPOUNDS | TPO, LPO, OGG1 | GAA 2008/4885KDM4E 896/4885MAPT 3781/4885 |
| US-20250375367-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TPMT, CRY1, TDP1 | GAA 3382/4885KDM4E 545/4885MAPT 90/4885 |
| US-20230404883-A1 | COSMETIC COMPOSITION COMPRISING NATURAL EMULSIFIERS AND THIOPYRIDINONE COMPOUNDS | PPARG, PHOSPHO1, POLQ | GAA 2225/4885KDM4E 1820/4885MAPT 3678/4885 |
| US-20250367096-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TPMT, DHPS, MTAP | GAA 3858/4885KDM4E 1341/4885MAPT 518/4885 |
| US-20250381115-A1 | STABILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TPMT, TPR, TYMP | GAA 3088/4885KDM4E 1410/4885MAPT 750/4885 |
| US-12226506-B2 | Cosmetic composition comprising natural emulsifiers and thiopyridinone compounds | PPARG, PHOSPHO1, POLQ | GAA 2225/4885KDM4E 1820/4885MAPT 3678/4885 |
| US-20250205131-A1 | COSMETIC COMPOSITION COMPRISING THIOPYRIDINONE COMPOUNDS, REDUCING AGENT AND ARGININE | PRMT1, ARG1, PRMT5 | GAA 4238/4885KDM4E 200/4885MAPT 1415/4885 |
| US-20250381116-A1 | SOLUBILIZATION OF THIOPYRIDINONE COMPOUND AND COMPOSITION COMPRISING SAME | TBCB, CCNB3, CYP24A1 | GAA 4523/4885KDM4E 1771/4885MAPT 2277/4885 |
| US-20230404879-A1 | ENHANCING PHOTOSTABILITY OF THIOPYRIDINONE COMPOUND WITHOUT THE USE OF UV FILTERS | TYR, TST, TSN | GAA 2602/4885KDM4E 209/4885MAPT 2465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.