Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15831228 | 0.85 | ALDH1A1 (0.75) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL8477018 | 0.82 | HPGD (0.61) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL12898776 | 0.81 | TSHR (0.44) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL21004152 | 0.80 | TSHR (0.80) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL13688925 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL10163441 | 0.79 | HPGD (0.65) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL885000 | 0.79 | MTNR1A (0.71) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL12884470 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL17152233 | 0.77 | HPGD (0.63) | ALDH1A1TSHRMEN1KMT2APOLB | |
| SCHEMBL10053738 | 0.77 | POLB (1.00) | ALDH1A1TSHRMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | PFIZER INC. | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028447-A1 | INDAZOLE DERIVATIVES | CNR1, CNR2, GPR119 | ALDH1A1 1172/4885TSHR 309/4885MEN1 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.