Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163441 | 0.87 | HPGD (0.65) | HPGDMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL59797 | 0.85 | ALDH1A1 (0.47) | HPGDMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL885000 | 0.83 | MTNR1A (0.71) | HPGDMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL2204065 | 0.83 | NPSR1 (0.64) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL12899396 | 0.82 | ALDH1A1 (0.64) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL13434069 | 0.80 | HPGD (0.69) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL2938380 | 0.80 | KMT2A (0.69) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL25189340 | 0.79 | HPGD (0.68) | HPGDMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL9187080 | 0.79 | MTNR1A (0.41) | HPGDMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL1520822 | 0.79 | NPSR1 (0.68) | HPGDMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749214-A | Containing 1,3 benzoxazole difluoro methylene indole ketone compounds and preparation method thereof | 上海大学 | 2017-05-31 | — | — | CN | disclosed |
| EP-2314598-A1 | Inhibitors of Hepatitis C virus NS3 serine protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-04-27 | — | — | EP | disclosed |
| US-5998091-A | COPOLYMER OF A MONOFUNCTIONAL MACROMONOMER HAVING A PARTICULAR POLYMERIZABLE DOUBLE BOND-CONTAINING GROUP SITUATED AT ONLY ONE END OF THE MAIN CHAIN, A QUATERNARY AMMONIUM SALT AND AN AMIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| US-4588656-A | Method of preparing a magnetic recording medium | FUJI PHOTO FILM CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |