Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 2/20 | 0.43 |
| ▸ | TK2 | O00142 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929848 | 1.00 | PYGM (0.49) | PYGMCYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL12731421 | 0.74 | TSHR (0.71) | PYGMP2RY6P2RY14TSHRLMNA | |
| SCHEMBL8922422 | 0.72 | ALDH1A1 (0.48) | PYGMBLMLMNATK1TK2 | |
| SCHEMBL8922939 | 0.72 | ALDH1A1 (0.48) | PYGMBLMLMNATK1TK2 | |
| SCHEMBL13907129 | 0.72 | KMT2A (0.48) | PYGMCYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL6839765 | 0.69 | PYGM (0.82) | PYGMP2RY6P2RY14TSHRLMNA | |
| SCHEMBL25824047 | 0.68 | PYGM (0.77) | PYGMP2RY6P2RY14TSHRLMNA | |
| SCHEMBL29725104 | 0.67 | PYGM (0.77) | PYGMP2RY6P2RY14TK1TK2 | |
| SCHEMBL2583339 | 0.67 | PYGM (0.77) | PYGMP2RY6P2RY14TK1TK2 | |
| SCHEMBL12315567 | 0.67 | PYGM (0.97) | PYGMP2RY6P2RY14TK1TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |