Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TK1 | P04183 | 4/20 | 0.42 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.36 |
| ▸ | TYMP | P19971 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12884518 | 0.79 | ALDH1A1 (0.36) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL12870930 | 0.74 | KMT2A (0.34) | KMT2AALDH1A1NPSR1 | |
| SCHEMBL12899786 | 0.72 | PYGM (0.49) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL12929848 | 0.72 | PYGM (0.49) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL12870924 | 0.71 | KMT2A (0.37) | KMT2AALDH1A1CNR1CNR2 | |
| SCHEMBL770144 | 0.70 | KMT2A (0.60) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL12870937 | 0.69 | KMT2A (0.36) | KMT2AALDH1A1NPSR1HTT | |
| SCHEMBL10769695 | 0.68 | TK1 (0.40) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL31087986 | 0.68 | CYP1A2 (0.50) | KMT2ACYP1A2GRIA1GRIA2GRIA4 | |
| SCHEMBL20088133 | 0.68 | CYP1A2 (0.57) | KMT2ACYP1A2GRIA1GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195459-B1 | NUCLEOBASE CHARACTERISATION | UNIV EDINBURGH (GB) | 2014-12-17 | — | — | EP | disclosed |
| WO-2009037473-A2 | NUCLEOBASE CHARACTERISATION | UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2009-03-26 | — | — | WO | disclosed |