SCHEMBL12899889

SCHEMBL12899889

CCOC[C@H]1O[C@@H](C)C(O)[C@H]1O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.36
FBP1 P09467 1/20 0.35
FUCA1 P04066 1/20 0.33
SELP P16109 1/20 0.33
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12929290 1.00 ADORA3 (0.36) ADORA3FBP1FUCA1SELPFYN
SCHEMBL16664704 0.98 FUCA1 (0.36) ADORA3FBP1FUCA1SELPFYN
SCHEMBL12179868 0.82 FBP1 (0.36) FBP1FUCA1SELP
SCHEMBL10000253 0.82
SCHEMBL5833176 0.81 ADORA3 (0.36) ADORA3FBP1SELPFYNMAOA
SCHEMBL26448837 0.79 CA2 (0.36) ADORA3FBP1SELPFYNMAOA
SCHEMBL7948962 0.79 LGALS1 (0.41) ADORA3FBP1
SCHEMBL30610704 0.79 CA2 (0.36) ADORA3FBP1SELPFYNMAOA
SCHEMBL26187985 0.79 IGF2R (0.42)
SCHEMBL24323044 0.78 OGA (0.40) ADORA3FBP1FUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7884202-B2 Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals TOSOH CORPORATION (JP) 2011-02-08 US disclosed