SCHEMBL12901606

SCHEMBL12901606

CCC(c1ccccc1N)C1C=CC=CC1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.32
AURKA O14965 1/20 0.31
PDPK1 O15530 1/20 0.31
RPS6KB1 P23443 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21065707 0.72 TSHR (0.40) AURKAPDPK1RPS6KB1ALDH1A1
SCHEMBL4649295 0.69 PKM (0.42) ALDH1A1
SCHEMBL10348301 0.68 SIGMAR1 (0.37) SIGMAR1ALDH1A1
SCHEMBL2495978 0.67 ALDH1A1 (0.45) ALDH1A1NOS3NOS1NOS2
SCHEMBL5948196 0.67 HRH1 (0.43) SIGMAR1ALDH1A1
SCHEMBL13287189 0.67
Ammonia Solution, Strong SCHEMBL25333625 0.66 ALDH1A1 (0.43) ALDH1A1NOS3NOS1NOS2
Hydrochloric Acid SCHEMBL27918612 0.66 ALDH1A1 (0.43) ALDH1A1NOS3NOS1NOS2
SCHEMBL13075295 0.66
SCHEMBL18849486 0.65 AURKA (0.35) SIGMAR1AURKAPDPK1RPS6KB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011014039-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-02-03 WO disclosed