Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324001 | 0.80 | KMT2A (0.42) | PKMCTDSP1KDM4EMEN1KMT2A | |
| SCHEMBL11335232 | 0.76 | SLC6A2 (0.41) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2465315 | 0.75 | PKM (0.62) | PKMCTDSP1GAAMEN1KMT2A | |
| SCHEMBL7368091 | 0.75 | MAPT (0.46) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL27391812 | 0.73 | PKM (0.59) | PKMCTDSP1GAAMEN1KMT2A | |
| Methyl Alcohol SCHEMBL27363776 | 0.70 | PKM (0.56) | PKMCTDSP1GAAMEN1KMT2A | |
| SCHEMBL5280802 | 0.70 | MAPT (0.41) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL26629764 | 0.69 | PKM (0.55) | PKMCTDSP1GAAMEN1KMT2A | |
| SCHEMBL12901606 | 0.69 | SIGMAR1 (0.32) | ALDH1A1 | |
| SCHEMBL22961730 | 0.69 | KCNA5 (0.44) | PKMCTDSP1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904047-A2 | APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007008627-A2 | APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2007-01-18 | — | — | WO | disclosed |