Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18580 | 0.81 | NR3C2 (0.64) | MEN1KMT2ANR3C2SMN1; SMN2GAA | |
| SCHEMBL9888564 | 0.80 | F2 (0.66) | MAPTMEN1KMT2APOLBSMN1; SMN2 | |
| Dimethylamine SCHEMBL7701402 | 0.79 | POLB (0.56) | MAPTMEN1HPGDKMT2APOLB | |
| Hydrochloric Acid SCHEMBL1807459 | 0.79 | NR3C2 (0.62) | MEN1KMT2ANR3C2SMN1; SMN2GAA | |
| Water SCHEMBL27466609 | 0.79 | NR3C2 (0.62) | MEN1KMT2ANR3C2SMN1; SMN2GAA | |
| Hydrogen Sulfide SCHEMBL27690671 | 0.79 | NR3C2 (0.62) | MEN1KMT2ANR3C2SMN1; SMN2GAA | |
| SCHEMBL11514359 | 0.79 | NR3C2 (0.62) | MEN1KMT2ANR3C2SMN1; SMN2GAA | |
| SCHEMBL7629070 | 0.78 | SMN1; SMN2 (0.80) | NR3C2SMN1; SMN2GAACA12CA2 | |
| SCHEMBL3906959 | 0.78 | NR3C2 (0.61) | MAPTMEN1KMT2ANR3C2SMN1; SMN2 | |
| SCHEMBL27094281 | 0.77 | POLB (0.69) | MAPTMEN1HPGDKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378326-A1 | Methods, Kits and Compositions Pertaining to the Suppression of the Detectable Probe Binding to Randomly Distributed Repeat Sequences Genomic Nucleic Acid | DAKO DENMARK APS (DK) | 2014-12-25 | — | — | US | disclosed |
| US-8754191-B2 | Methods, kits and compositions pertaining to the suppression of the detectable probe binding to randomly distributed repeat sequences genomic nucleic acid | BOSTON PROBES, INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20130150264-A1 | Methods, Kits and Compositions Pertaining to the Suppression of the Detectable Probe Binding to Randomly Distributed Repeat Sequences Genomic Nucleic Acid | Life Technologies Corporation (US) | 2013-06-13 | — | — | US | disclosed |
| US-20110306520-A1 | Methods, Kits and Compositions Pertaining to the Suppression of the Detectable Probe Binding to Randomly Distributed Repeat Sequences Genomic Nucleic Acid | Life Technologies Corporation (US) | 2011-12-15 | — | — | US | disclosed |
| US-7884053-B2 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-7851155-B2 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2010-12-14 | — | — | US | disclosed |
| US-20100190660-A1 | Methods, Compositions And Libraries Pertaining To PNA Dimer And PNA Oligomer Synthesis | BOSTON PROBES, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| US-7745126-B2 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7674585-B2 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2010-03-09 | — | — | US | disclosed |
| US-7638279-B2 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2009-12-29 | — | — | US | disclosed |
| US-7605253-B2 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7566420-B1 | Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation | BOSTON PROBES, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| US-20090163381-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA CORPORATION. (US) | 2009-06-25 | — | — | US | disclosed |
| US-20080269074-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA CORPORATION (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080220987-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA CORPORATION. (US) | 2008-09-11 | — | — | US | disclosed |
| US-20080206747-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA COPORATION (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080125332-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA CORPORATION. (US) | 2008-05-29 | — | — | US | disclosed |
| US-20080085837-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA CORPORATION (US) | 2008-04-10 | — | — | US | disclosed |
| US-20070105145-A1 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation | APPLERA CORPORATION (US) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190660-A1 | Methods, Compositions And Libraries Pertaining To PNA Dimer And PNA Oligomer Synthesis | NCL, RNGTT, SSB | MAPT 1205/4885MEN1 3323/4885HPGD 3619/4885 |
| US-20110306520-A1 | Methods, Kits and Compositions Pertaining to the Suppression of the Detectable Probe Binding to Randomly Distributed Repeat Sequences Genomic Nucleic Acid | UNG, RNGTT, DNTT | MAPT 2649/4885MEN1 2339/4885HPGD 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.