SCHEMBL9888564

SCHEMBL9888564

CNS(=O)(=O)c1ccc(/N=N/c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.66
PRSS1 P07477 3/20 0.66
PRSS2 P07478 3/20 0.66
PRSS3 P35030 3/20 0.66
CA9 Q16790 4/20 0.65
CA12 O43570 3/20 0.65
CA2 P00918 3/20 0.65
NPC1 O15118 3/20 0.65
MEN1 O00255 2/20 0.65
POLB P06746 2/20 0.65
RAB9A P51151 2/20 0.65
KMT2A Q03164 2/20 0.65
ALDH1A1 P00352 6/20 0.56
TSHR P16473 3/20 0.56
ALOX15 P16050 1/20 0.56
MAPK1 P28482 4/20 0.52
TDP1 Q9NUW8 4/20 0.52
HSD17B10 Q99714 2/20 0.52
MAPT P10636 3/20 0.49
LMNA P02545 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27872854 0.89 CA9 (0.61) F2PRSS1PRSS2PRSS3CA9
SCHEMBL9719462 0.85 F2 (0.68) F2PRSS1PRSS2PRSS3CA9
SCHEMBL23808946 0.82 F2 (0.61) F2PRSS1PRSS2PRSS3CA9
SCHEMBL14176753 0.82 F2 (0.61) F2PRSS1PRSS2PRSS3CA9
SCHEMBL15631068 0.82 NPC1 (0.73) F2PRSS1PRSS2PRSS3CA9
SCHEMBL13384871 0.80 NPC1 (0.71) F2PRSS1PRSS2PRSS3CA9
SCHEMBL12901867 0.80 MAPT (0.61) F2PRSS1PRSS2PRSS3CA9
SCHEMBL14419936 0.80 NPC1 (0.71) F2PRSS1PRSS2PRSS3CA9
SCHEMBL9019288 0.80 NPC1 (0.71) F2PRSS1PRSS2PRSS3CA9
SCHEMBL13602555 0.80 NPC1 (0.71) F2PRSS1PRSS2PRSS3CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013999-A1 NON-NUCLEOSIDIC SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE SYNTHESIS AM CHEMICALS LLC (US) 2018-01-18 WO disclosed
US-20120141402-A1 NANOSCOPIC HAIR CARE PRODUCTS BOSTON COSMETICS, LLC 2012-06-07 US disclosed
US-7968084-B2 A Hair dye IN AN INTIMATE RELATIONSHIP TO A POLYMERIC NANOSTRUCTURE having hair-reactive functional groups to be covalently bound to or immobilized onto or in the hair BOSTON COSMETICS, LLC (US) 2011-06-28 US disclosed
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same CREDIA JAPAN CO., LTD. (JP) 2008-06-12 US disclosed
US-7282575-B2 Functional peptide nucleic acid monomer and process for producing the same CREDIA JAPAN CO., LTD. (JP) 2007-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same NSUN3, RNGTT, NSUN2 F2 2109/4885PRSS1 4194/4885PRSS2 3342/4885
US-20120141402-A1 NANOSCOPIC HAIR CARE PRODUCTS TYR, CUTA, SUCLG1 F2 942/4885PRSS1 2956/4885PRSS2 1867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.