Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48731 | 0.92 | POLB (0.64) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL48732 | 0.92 | POLB (0.64) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL9620534 | 0.84 | HSD17B10 (0.52) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL15704429 | 0.81 | CA2 (0.69) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| Dimethylamine SCHEMBL3698119 | 0.79 | ALDH1A1 (0.71) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL12901867 | 0.79 | MAPT (0.61) | POLBCYP2D6ALDH1A1MAPTMEN1 | |
| SCHEMBL10767433 | 0.79 | CA12 (0.43) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL10767423 | 0.78 | POLB (0.41) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| SCHEMBL10767429 | 0.78 | POLB (0.41) | POLBCYP2D6ALDH1A1TDP1HSD17B10 | |
| Azobenzene SCHEMBL9551792 | 0.77 | ALDH1A1 (0.67) | POLBCYP2D6ALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208109-A2 | NUCLEOSIDE ANALOGUES | NYCOMED AMERSHAM PLC (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001016150-A2 | NUCLEOSIDE ANALOGUES | AMERSHAM PLC (GB) | 2001-03-08 | — | — | WO | disclosed |