Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.58 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | UBE2N | P61088 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10313738 | 0.86 | ALOX5 (0.64) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL30689046 | 0.80 | ALOX5 (0.65) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL22638205 | 0.80 | ALOX5 (0.65) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL28709439 | 0.78 | HDAC1 (0.69) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL13302218 | 0.77 | ALOX5 (0.68) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL12908807 | 0.77 | HTR6 (0.62) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL949348 | 0.76 | LMNA (0.82) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL29414776 | 0.76 | AKR1C3 (0.78) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL12748306 | 0.76 | AKR1C3 (0.78) | ALOX5PTGS2HTR6KDM4EUBE2N | |
| SCHEMBL10002866 | 0.76 | ALOX5 (0.58) | ALOX5PTGS2HTR6KDM4EUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016528-A1 | AMINOPYRAZOLE DERIVATIVE | 中外製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |