SCHEMBL12909396

SCHEMBL12909396

N#COc1ccc(C(c2ccc(N=C=O)cc2)c2ccc(N=C=O)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 2/20 0.39
▸ TSHR P16473 1/20 0.39
▸ MAPK1 P28482 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ TRPA1 O75762 1/20 0.32
▸ CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20045932 1.00 CYP3A4 (0.39) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL15362533 0.94 CYP3A4 (0.35) CYP3A4TSHRMAPK1TDP1
SCHEMBL34741 0.89 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL13084803 0.87 CYP3A4 (0.37) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL15981020 0.84 CYP3A4 (0.42) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL10033172 0.84 CYP3A4 (0.42) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL17320306 0.82 CYP3A4 (0.44) CYP3A4TSHRCYP1A2
SCHEMBL3225154 0.82 SLC2A1 (0.38) —
SCHEMBL93536 0.82 CYP3A4 (0.54) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL16383172 0.80 CYP3A4 (0.52) CYP3A4TSHRMAPK1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159692-A1 VEHICLE WIPER BLADE CANON KABUSHIKI KAISHA (JP) 2023-05-25 — — US disclosed
US-20230157493-A1 WIPER BLADE CANON KABUSHIKI KAISHA (JP) 2023-05-25 — — US disclosed
US-20230159001-A1 VEHICLE WINDSHIELD WIPER BLADE CANON KABUSHIKI KAISHA (JP) 2023-05-25 — — US disclosed
US-20230157492-A1 CLEANING WIPER BLADE CANON KABUSHIKI KAISHA (JP) 2023-05-25 — — US disclosed
US-9994516-B2 Flexible to rigid nanoporous polyurethane-acrylate (PUAC) type materials for structural and thermal insulation applications THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2018-06-12 — — US disclosed
US-9904188-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-02-27 — — US disclosed
US-9772569-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-26 — — US disclosed
US-9760030-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-12 — — US disclosed
US-9726992-B2 Electrophotographic photosensitive member, manufacturing method of electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-08-08 — — US disclosed
US-20170137376-A1 FLEXIBLE TO RIGID NANOPOROUS POLYURETHANE-ACRYLATE (PUAC) TYPE MATERIALS FOR STRUCTURAL AND THERMAL INSULATION APPLICATIONS THE CURATORS OF THE UNIVERSITY OF MISSOURI 2017-05-18 — — US disclosed
US-9029054-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-05-12 — — US disclosed
US-20150111976-A1 MULTIFUNCTIONAL POROUS ARAMIDS (AEROGELS) AND FABRICATION THEREOF THE CURATORS OF THE UNIVERSITY OF MISSOURI 2015-04-23 — — US disclosed
US-20150099218-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-09 — — US disclosed
US-8940465-B2 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and imide compound CANON KABUSHIKI KAISHA (JP) 2015-01-27 — — US disclosed
US-20140377701-A1 PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2014-12-25 — — US disclosed
US-8877824-B2 Multifunctional porous aramids (aerogels) and fabrication thereof THE CURATORS OF THE UNIVERSITY OF MISSOURI 2014-11-04 — — US disclosed
US-8735528-B1 Two-photon absorbing cross-linked polyurethanes containing diphenylamino-dialkylfluorene-1,3,5-triazine units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2014-05-27 — — US disclosed
US-20130085290-A1 METHODS AND COMPOSITIONS FOR PREPARING SILICA AEROGELS AEROGEL TECHNOLOGIES, LLC (US) 2013-04-04 — — US disclosed
US-8318888-B1 Two-photon absorbing cross-linked polyurethanes containing delphenylamino-dialkyffluorene-1,3,5-triazine units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2012-11-27 — — US disclosed
US-20110020591-A1 TREATMENT COMPRISING WATER- AND OIL-REPELLENT AGENT DAIKIN INDUSSRIES, LTD. (JP) 2011-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111976-A1 MULTIFUNCTIONAL POROUS ARAMIDS (AEROGELS) AND FABRICATION THEREOF PFAS, AAAS, FADS1 CYP3A4 3109/4885TSHR 4869/4885MAPK1 4720/4885
US-20130085290-A1 METHODS AND COMPOSITIONS FOR PREPARING SILICA AEROGELS STOM, RAD54L, MTCL3 CYP3A4 3965/4885TSHR 4872/4885MAPK1 4778/4885
US-20170137376-A1 FLEXIBLE TO RIGID NANOPOROUS POLYURETHANE-ACRYLATE (PUAC) TYPE MATERIALS FOR STRUCTURAL AND THERMAL INSULATION APPLICATIONS PUF60, FUS, UFM1 CYP3A4 4014/4885TSHR 4072/4885MAPK1 4232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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