SCHEMBL129094

SCHEMBL129094

[CH2]Cc1cccc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL400182 0.81 TAAR1 (0.63)
SCHEMBL1807040 0.81 GRIN2D (0.42)
SCHEMBL1145829 0.80
SCHEMBL3300276 0.79 PNMT (0.65)
SCHEMBL12050856 0.79 TAAR1 (0.74)
SCHEMBL28404628 0.78 CYP3A4 (0.69)
SCHEMBL900927 0.78 HTR3E (0.59)
SCHEMBL29355341 0.77
SCHEMBL28529008 0.77
SCHEMBL195102 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103351-A Coronavirus inhibitors 共晶制药公司 2024-05-28 CN claimed
US-20240150318-A1 PROTEASE INHIBITORS FOR TREATMENT OF CORONAVIRUS INFECTIONS THE SCRIPPS RESEARCH INSTITUTE 2024-05-09 US claimed
EP-4352040-A1 PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS The Scripps Research Institute (US) 2024-04-17 EP claimed
CN-117794896-A Protease inhibitors for the treatment of coronavirus infections 斯克里普斯研究学院 2024-03-29 CN claimed
WO-2022261473-A1 PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS THE SCRIPPS RESEARCH INSTITUTE (US) 2022-12-15 WO claimed
CN-115260834-A Sulfur-containing high-refractive-index ink composition and preparation method thereof 西安思摩威新材料有限公司 2022-11-01 CN claimed
CN-112867706-A MASP-2 inhibitors and methods of use 奥默罗斯公司 2021-05-28 CN claimed
CN-109503405-B Synthesis method of N-N-propyl amide 中国农业大学 2021-04-16 CN claimed
EP-3802489-A2 MASP-2 INHIBITORS AND METHODS OF USE Omeros Corporation (US) 2021-04-14 EP claimed
EP-3728235-A1 SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS Syngenta Crop Protection AG (CH) 2020-10-28 EP claimed
WO-2001025203-A1 PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-04-12 WO claimed
WO-2001009088-A1 UREA DERIVATIVES AS INHIBITORS OF CCR-3 RECEPTOR KIRIN BEER KABUSHIKI KAISHA (JP) 2001-02-08 WO claimed
WO-2000069816-A1 METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2000-11-23 WO claimed
WO-2000061646-A1 WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS SURGIDEV CORPORATION (US) 2000-10-19 WO claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO claimed
US-6060453-A Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose GREENWICH PHARMACEUTICALS INCORPORATED (US) 2000-05-09 US claimed
EP-0977754-A1 WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA Ciba SC Holding AG (CH) 2000-02-09 EP claimed
WO-1998049164-B1 WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA 1998-12-03 WO claimed
WO-1998049164-A1 WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-11-05 WO claimed
US-5120849-A Reacting cyclic imidoether with aminoalcohol BASF AKTIENGESELLSCHAFT (DE) 1992-06-09 US claimed