SCHEMBL1290964

SCHEMBL1290964

CCCCCCC(=O)NO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 1.00
HDAC3 O15379 2/20 0.75
HDAC1 Q13547 2/20 0.75
HDAC2 Q92769 2/20 0.75
HDAC8 Q9BY41 2/20 0.75
HDAC6 Q9UBN7 2/20 0.75
HDAC5 Q9UQL6 1/20 0.75
FAAH O00519 4/20 0.64
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
MAPK1 P28482 1/20 0.59
CES2 O00748 3/20 0.56
CES1 P23141 3/20 0.56
PPARG P37231 4/20 0.54
PPARD Q03181 4/20 0.54
PPARA Q07869 4/20 0.54
TSHR P16473 3/20 0.54
GPR84 Q9NQS5 3/20 0.54
HDAC11 Q96DB2 3/20 0.54
ALDH1A1 P00352 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL572646 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL2403692 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL331039 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL4155670 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL7945790 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL23203038 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL5575814 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL20915286 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL20602650 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8
SCHEMBL8977849 1.00 HSP90AA1 (1.00) HSP90AA1HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3350313-B1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2025-11-26 EP claimed
US-20250297134-A1 HIGH RATE BULK OXIDE CMP COMPOSITION ENTEGRIS, INC. 2025-09-25 US claimed
US-12415904-B2 Biobased glyceryl heptanoate ester compositions and methods of making and using the same INOLEX INVESTMENT CORPORATION (US) 2025-09-16 US claimed
CN-110066281-B Multi-target anti-tumor activity evodiamine derivative, and preparation method and application thereof 中国人民解放军第二军医大学 2024-01-30 CN claimed
CN-116554079-B Histone deacetylase inhibitor and application thereof 南京市鸿舜医药科技有限公司 2023-11-10 CN claimed
EP-4240314-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME Inolex Investment Corporation (US) 2023-09-13 EP claimed
CN-116554079-A Histone deacetylase inhibitor and application thereof 南京市鸿舜医药科技有限公司 2023-08-08 CN claimed
CN-114105958-B Hydroximic acid-containing 2-phenylamino pyrimidine derivatives and application thereof 郑州大学第一附属医院 2022-11-22 CN claimed
CN-113387840-B PD-1/PD-L1 and HDACs double-target inhibitor, preparation method and application 中国药科大学 2022-11-08 CN claimed
CN-109879790-B Amide micromolecule organic compound with indole or indole analogue as mother nucleus structure, application and preparation method thereof 华东师范大学 2022-09-20 CN claimed
WO-2022098829-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME INOLEX INVESTMENT CORPORATION (US) 2022-05-12 WO claimed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US claimed
US-20220135769-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME INOLEX INVESTMENT CORPORATION (US) 2022-05-05 US claimed
CN-114105958-A Hydroximic acid-containing 2-phenylamino pyrimidine derivatives and application thereof 郑州大学第一附属医院 2022-03-01 CN claimed
CN-111632749-A Beneficiation method for recovering copper oxide from copper oxide acid leaching residues 西北矿冶研究院 2020-09-08 CN claimed
CN-111632746-A Beneficiation method for improving copper recovery rate of copper oxide acid leaching residue 西北矿冶研究院 2020-09-08 CN claimed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US claimed
CN-1028227-C Pharmacologically active 1,5-diarly-3-substituted-pyrazoles and method for synthesizing the same ORTHO PHARMA CORP (US) 1995-04-19 CN claimed
CN-87103953-A Pharmaceutically active 1, 5-diaryl-3-substituted pyrazoles and synthesis method thereof 1987-12-09 CN claimed
US-4579844-A APPLYING AN ARYLACETOHYDROXAMIC ACID DERIVATIVE JOHNSON & JOHNSON (US) 1986-04-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415904-B2 Biobased glyceryl heptanoate ester compositions and methods of making and using the same SGMS1, MGLL, CCL11 HSP90AA1 1742/4885HDAC3 3593/4885HDAC1 3853/4885
US-20220135769-A1 BIOBASED GLYCERYL HEPTANOATE ESTER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME SGMS1, MGLL, CCL11 HSP90AA1 1742/4885HDAC3 3593/4885HDAC1 3853/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 HSP90AA1 3362/4885HDAC3 3798/4885HDAC1 1616/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 HSP90AA1 3362/4885HDAC3 3798/4885HDAC1 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.