Trolamine

Trolamine

SCHEMBL129129

COS(=O)(=O)OC.OCCN(CCO)CCO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALOX15 P16050 1/20 0.32
USP2 O75604 1/20 0.30
TSHR P16473 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL8742002 0.98 MAPT (0.32) MAPTSMN1; SMN2KDM4EALOX15
Trolamine SCHEMBL37853 0.85 MAPT (0.33) MAPTSMN1; SMN2KDM4EALOX15USP2
Trolamine SCHEMBL11787722 0.81 CA1 (0.32) MAPTSMN1; SMN2KDM4EALOX15
Sulfuric Acid Dimethyl Ester SCHEMBL28213915 0.81 TSHR (0.39) USP2TSHR
SCHEMBL24075532 0.79
Trolamine SCHEMBL29245635 0.78 MAPT (0.44) MAPTSMN1; SMN2KDM4EALOX15CYP1A2
SCHEMBL28706832 0.78 NPSR1 (0.31)
SCHEMBL28672601 0.76 MAPT (0.34) MAPTSMN1; SMN2KDM4EALOX15
Trolamine SCHEMBL9827519 0.76 MAPT (0.38) MAPTSMN1; SMN2KDM4EALOX15CYP1A2
Trolamine SCHEMBL4654746 0.75 CA5A (0.40) MAPTSMN1; SMN2KDM4EALOX15CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630784-B2 Formula design for a solid laundry fabric softener ECOLAB USA INC. (US) 2026-05-19 US claimed
US-20240060009-A1 FORMULA DESIGN FOR A SOLID LAUNDRY FABRIC SOFTENER ECOLAB USA INC. 2024-02-22 US claimed
US-12630784-B2 Formula design for a solid laundry fabric softener ECOLAB USA INC. (US) 2026-05-19 US disclosed
EP-4370638-B1 CATIONIC NONIONIC BLENDS FOR CLEANING OILY SOILS ECOLAB USA INC (US) 2026-05-13 EP disclosed
EP-4722327-A2 CATIONIC NONIONIC BLENDS FOR CLEANING OILY SOILS Ecolab USA Inc. (US) 2026-04-08 EP disclosed
US-12595437-B2 Cationic nonionic blends for cleaning oily soils ECOLAB USA INC. (US) 2026-04-07 US disclosed
US-20250290010-A1 HIGHLY ACIDIC LAUNDRY SOUR SOFTENER WITH EXTRA STABILITY, LAUNDRY FIRE MITIGATION, AND OILY SOIL REMOVAL PROPERTIES ECOLAB USA INC. 2025-09-18 US disclosed
US-12344818-B2 Highly acidic laundry sour softener with extra stability, laundry fire mitigation, and oily soil removal properties ECOLAB USA INC. (US) 2025-07-01 US disclosed
US-12163108-B2 Solid laundry softener composition ECOLAB USA INC. (US) 2024-12-10 US disclosed
EP-4370638-A1 CATIONIC NONIONIC BLENDS FOR CLEANING OILY SOILS Ecolab USA Inc. (US) 2024-05-22 EP disclosed
US-20240060009-A1 FORMULA DESIGN FOR A SOLID LAUNDRY FABRIC SOFTENER ECOLAB USA INC. 2024-02-22 US disclosed
EP-1190035-A1 FABRIC CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2002-03-27 EP disclosed
WO-2002020707-A2 FABRIC CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2002-03-14 WO disclosed
WO-2002020706-A1 A METHOD OF PREPARING FABRIC CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2002-03-14 WO disclosed
WO-2001096510-A1 FABRIC SOFTENING COMPOSITIONS UNILEVER PLC (GB) 2001-12-20 WO disclosed
WO-2001092447-A1 FABRIC CONDITIONING COMPOSITION UNILEVER PLC (GB) 2001-12-06 WO disclosed
WO-2001059052-A1 FABRIC CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2001-08-16 WO disclosed
WO-2001059200-A1 FABRIC CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2001-08-16 WO disclosed
WO-2001004254-A1 FABRIC CONDITIONING COMPOSITIONS UNILEVER PLC (GB) 2001-01-18 WO disclosed
CN-1145392-A Screen electrostatic ray eliminating agent JIANG HAI (CN) 1997-03-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630784-B2 Formula design for a solid laundry fabric softener SLC43A1, CLK4, CLK1 MAPT 3792/4885SMN1; SMN2 1603/4885KDM4E 1945/4885
US-12595437-B2 Cationic nonionic blends for cleaning oily soils SAT1, SIGMAR1, PHOSPHO1 MAPT 4286/4885SMN1; SMN2 1414/4885KDM4E 1029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.