Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 9/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913014 | 0.72 | CNR2 (0.70) | MAPTATMCNR1ACHECNR2 | |
| SCHEMBL12912991 | 0.70 | CYP3A4 (0.41) | ACHE | |
| SCHEMBL12913013 | 0.69 | CNR2 (0.45) | MAPTATMCNR1ACHECNR2 | |
| SCHEMBL7808408 | 0.69 | CNR2 (0.45) | MAPTCNR1ACHECNR2MEN1 | |
| SCHEMBL30302187 | 0.69 | RORC (0.54) | SLC9A1HTR6MEN1KMT2AHTT | |
| SCHEMBL12912994 | 0.68 | BCHE (0.45) | CNR1ACHECNR2MEN1KMT2A | |
| SCHEMBL7808406 | 0.68 | MAPT (0.37) | MAPTATMCNR1ACHECNR2 | |
| SCHEMBL9980554 | 0.67 | SLC9A1 (0.45) | SLC9A1HTR6IDEMEN1KMT2A | |
| SCHEMBL7811883 | 0.67 | CNR2 (0.58) | CNR1ACHECNR2CA12CA1 | |
| SCHEMBL12913017 | 0.67 | CNR2 (0.42) | MAPTATMCNR1ACHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776345-B1 | Method of preparing N2-functionalised indazolinone derivatives | UNIV ST ANDREWS (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-7868184-B2 | Multicore indazolinone library | The University of the University of St. Andrews (GB) | 2011-01-11 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
| US-20070179294-A1 | Multicore indazolinone library | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179294-A1 | Multicore indazolinone library | IPMK, TTK, IWS1 | SLC9A1 4773/4885MAPT 2038/4885ATM 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.