Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5791833 | 0.98 | TERT (0.43) | TERTNPC1RAB9AMAPTMEN1 | |
| SCHEMBL1470931 | 0.95 | TERT (0.53) | TERTNPC1RAB9AMAPTMEN1 | |
| SCHEMBL5724692 | 0.94 | PSMB5 (0.43) | TERTNPC1RAB9AMAPTMEN1 | |
| SCHEMBL1472495 | 0.94 | TERT (0.40) | TERTNPC1RAB9AMAPTMEN1 | |
| Iodide SCHEMBL1470324 | 0.94 | TERT (0.51) | TERTNPC1RAB9AMAPTMEN1 | |
| Iodide SCHEMBL1470298 | 0.92 | TERT (0.39) | TERTNPC1RAB9AMAPTMEN1 | |
| Iodide SCHEMBL1470285 | 0.92 | PSMB5 (0.42) | TERTNPC1RAB9AMAPTMEN1 | |
| SCHEMBL1472472 | 0.92 | TERT (0.39) | TERTNPC1RAB9AMAPTMEN1 | |
| SCHEMBL1470384 | 0.91 | TERT (0.38) | TERTNPC1RAB9AMAPTMEN1 | |
| Iodide SCHEMBL1471043 | 0.91 | NPC1 (0.43) | TERTNPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| US-9765042-B2 | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-09-19 | — | — | US | disclosed |
| US-9765042-B2 | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-09-19 | — | — | US | disclosed |
| US-20170209456-A1 | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-07-27 | — | — | US | disclosed |
| US-20170209456-A1 | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-07-27 | — | — | US | disclosed |
| US-9675621-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2017-06-13 | — | — | US | disclosed |
| US-9555043-B2 | High purity diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-01-31 | — | — | US | disclosed |
| US-9555043-B2 | High purity diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-01-31 | — | — | US | disclosed |
| US-20160296531-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2016-10-13 | — | — | US | disclosed |
| US-9242946-B2 | High purity diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2016-01-26 | — | — | US | disclosed |
| US-8691979-B2 | Methods of chemical synthesis of diaminophenothiazinium compounds involving the use of persulfate oxidants | WISTA LABORATORIES LTD. (SG) | 2014-04-08 | — | — | US | disclosed |
| US-8440821-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2013-05-14 | — | — | US | disclosed |
| US-20120058995-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | WISTA LABORATORIES LTD. (SG) | 2012-03-08 | — | — | US | disclosed |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. | 2011-12-01 | — | — | US | disclosed |
| US-7956183-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2011-06-07 | — | — | US | disclosed |
| US-20110021510-A1 | METHODS OF CHEMICAL SYNTHESIS AND PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INCLUDING METHYLTHIONINIUM CHLORIDE (MTC) | WISTA LABORATORIES LTD. | 2011-01-27 | — | — | US | disclosed |
| US-7790881-B2 | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2010-09-07 | — | — | US | disclosed |
| US-20090259040-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2009-10-15 | — | — | US | disclosed |
| US-20080207603-A1 | Methods of Chemical Synthesis and Purification of Diaminophenothiazinium Compounds Including Methylthioninium Chloride (Mtc) | WISTA LABORATORIES LTD. | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | TERT 600/4885NPC1 2397/4885RAB9A 2788/4885 |
| US-20080207603-A1 | Methods of Chemical Synthesis and Purification of Diaminophenothiazinium Compounds Including Methylthioninium Chloride (Mtc) | MGMT, MAPT, CRBN | TERT 10/4885NPC1 1785/4885RAB9A 1714/4885 |
| US-20090259040-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | PARK7, SNCA, GRN | TERT 96/4885NPC1 1131/4885RAB9A 2529/4885 |
| US-20170209456-A1 | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | MGMT, TST, MAPT | TERT 7/4885NPC1 2621/4885RAB9A 3732/4885 |
| US-20120058995-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | TST, TPMT, MGMT | TERT 61/4885NPC1 4051/4885RAB9A 3655/4885 |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MMAB, MB, ABCB7 | TERT 743/4885NPC1 1959/4885RAB9A 3116/4885 |
| US-20110021510-A1 | METHODS OF CHEMICAL SYNTHESIS AND PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INCLUDING METHYLTHIONINIUM CHLORIDE (MTC) | MGMT, TST, MAPT | TERT 11/4885NPC1 2426/4885RAB9A 4065/4885 |
| US-20160296531-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | TERT 600/4885NPC1 2397/4885RAB9A 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.