SCHEMBL12919637

SCHEMBL12919637

CCC(=O)NCCCCC(NC(C)C)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ FOLH1 Q04609 8/20 0.42
▸ NOD1 Q9Y239 2/20 0.39
▸ ALB P02768 2/20 0.39
▸ RECQL P46063 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ EPHX2 P34913 1/20 0.37
▸ EPHX1 P07099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15160764 0.86 KMT2A (0.49) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL15160683 0.86 KMT2A (0.49) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL763069 0.86 MEN1 (0.53) MEN1KMT2AFOLH1ALBRECQL
SCHEMBL24796610 0.84 NOD1 (0.58) NOD1EPHX2
SCHEMBL14217259 0.83 MEN1 (0.59) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL16384384 0.83 MEN1 (0.59) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL13197601 0.83 MEN1 (0.59) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL16384378 0.83 MEN1 (0.59) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL20806790 0.83 FOLH1 (0.40) MEN1KMT2AFOLH1NOD1ALB
SCHEMBL18116882 0.82 MEN1 (0.57) MEN1KMT2AFOLH1NOD1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8653049-B2 Normuramyl glycopeptide compounds IMUTHES LIMITED (GB) 2014-02-18 — — US disclosed
US-20110002983-A1 COMPOUND IMUTHES LIMITED (GB) 2011-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110002983-A1 COMPOUND C5AR1, C5AR2, ARG1 MEN1 683/4885KMT2A 713/4885FOLH1 2429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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