Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | IKBKB | O14920 | 5/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12924253 | 1.00 | ESR1 (0.42) | ESR1ESR2MAPK14IKBKBCHUK | |
| SCHEMBL12924264 | 0.88 | LMNA (0.39) | ESR1ESR2MAPK14IKBKBCHUK | |
| SCHEMBL12924308 | 0.84 | HSD17B1 (0.46) | ESR1ESR2HSD17B1HSD17B2MAPT | |
| SCHEMBL12924298 | 0.81 | ESR1 (0.42) | ESR1ESR2HSD17B1HSD17B2MAPT | |
| SCHEMBL12924310 | 0.81 | HSD17B1 (0.47) | ESR1ESR2IKBKBCYP1A2CYP3A4 | |
| SCHEMBL12924307 | 0.81 | ESR1 (0.42) | ESR1ESR2HSD17B1HSD17B2MAPT | |
| SCHEMBL12924306 | 0.81 | HSD17B1 (0.50) | ESR1ESR2IKBKBCYP1A2CYP3A4 | |
| SCHEMBL12924272 | 0.81 | HSD17B1 (0.50) | ESR1ESR2IKBKBCYP1A2CYP3A4 | |
| SCHEMBL13556975 | 0.80 | HTR2C (0.36) | ESR1MAPK14HSD17B1HSD17B2 | |
| SCHEMBL12924351 | 0.80 | NR3C1 (0.43) | CYP3A4HSD17B1HSD17B2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259355-B1 | ORGANIC TRANSISTOR | YAMAMOTO CHEMICALS INC (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-8294144-B2 | Organic transistor | YAMAMOTO CHEMICALS, INC. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-8294144-B2 | Organic transistor | YAMAMOTO CHEMICALS, INC. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20110012098-A1 | ORGANIC TRANSISTOR | YAMAMOTO CHEMICALS, INC. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20110012098-A1 | ORGANIC TRANSISTOR | YAMAMOTO CHEMICALS, INC. (JP) | 2011-01-20 | — | — | US | disclosed |