Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12924253 | 0.80 | ESR1 (0.42) | HSD17B1HSD17B2MAPK14ESR1 | |
| SCHEMBL12924324 | 0.80 | ESR1 (0.42) | HSD17B1HSD17B2MAPK14ESR1 | |
| SCHEMBL12924308 | 0.76 | HSD17B1 (0.46) | HSD17B1HSD17B2ESR1 | |
| SCHEMBL12924351 | 0.71 | NR3C1 (0.43) | HSD17B1HSD17B2 | |
| SCHEMBL12924310 | 0.71 | HSD17B1 (0.47) | HSD17B1HSD17B2ESR1 | |
| SCHEMBL12924272 | 0.71 | HSD17B1 (0.50) | HSD17B1HSD17B2ESR1 | |
| SCHEMBL12924306 | 0.71 | HSD17B1 (0.50) | HSD17B1HSD17B2ESR1 | |
| SCHEMBL12924264 | 0.70 | LMNA (0.39) | MAPK14ESR1 | |
| SCHEMBL12924238 | 0.68 | HSD17B1 (0.47) | HSD17B1HSD17B2ESR1TSHR | |
| SCHEMBL12924255 | 0.67 | ESR1 (0.43) | HSD17B1HSD17B2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8294144-B2 | Organic transistor | YAMAMOTO CHEMICALS, INC. (JP) | 2012-10-23 | — | — | US | disclosed |