Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300148 | 0.89 | LMNA (0.38) | THRBLMNAL3MBTL1 | |
| SCHEMBL8025665 | 0.84 | LMNA (0.38) | THRBLMNAL3MBTL1 | |
| SCHEMBL10874803 | 0.76 | MGAM (0.41) | THRBALDH1A1TSHRLMNA | |
| SCHEMBL14866617 | 0.76 | LMNA (0.50) | THRBLMNAL3MBTL1 | |
| SCHEMBL12928873 | 0.74 | LMNA (0.35) | THRBLMNAL3MBTL1 | |
| SCHEMBL12928872 | 0.74 | CYP2D6 (0.39) | THRBALDH1A1LMNAL3MBTL1 | |
| SCHEMBL14928286 | 0.71 | LMNA (0.43) | THRBLMNAL3MBTL1 | |
| SCHEMBL3441481 | 0.71 | AKR1B1 (0.34) | — | |
| SCHEMBL12928866 | 0.71 | — | — | |
| SCHEMBL546820 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |