⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21019700 | 0.73 | MGLL (0.42) | — | |
| SCHEMBL20132373 | 0.69 | MGLL (0.46) | — | |
| SCHEMBL20132050 | 0.69 | MGLL (0.39) | — | |
| SCHEMBL18594707 | 0.69 | — | — | |
| SCHEMBL20420335 | 0.69 | — | — | |
| SCHEMBL18594686 | 0.65 | MGLL (0.36) | — | |
| SCHEMBL22223456 | 0.63 | DDAH1 (0.35) | — | |
| SCHEMBL18596572 | 0.62 | — | — | |
| SCHEMBL36966 | 0.62 | — | — | |
| SCHEMBL18594671 | 0.61 | GSK3A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240230660-A1 | PROTEIN MELT ANALYSIS USING DIPYRROMETHENEBORON DIFLUORIDE COMPOUNDS | LIFE TECHNOLOGIES CORP (US) | 2024-07-11 | — | — | US | disclosed |
| US-11841370-B2 | Protein melt analysis using dipyrrometheneboron difluoride compounds | Life Technologies Corporation (US) | 2023-12-12 | — | — | US | disclosed |
| US-20220026437-A1 | PROTEIN MELT ANALYSIS USING DIPYRROMETHENEBORON DIFLUORIDE COMPOUNDS | Life Technologies Corporation | 2022-01-27 | — | — | US | disclosed |
| US-20190339280-A1 | PROTEIN MELT ANALYSIS USING DIPYRROMETHENEBORON DIFLUORIDE COMPOUNDS | Life Technologies Corporation | 2019-11-07 | — | — | US | disclosed |
| US-10401366-B2 | Protein melt analysis using dipyrrometheneboron difluoride compounds | Life Technologies Corporation (US) | 2019-09-03 | — | — | US | disclosed |
| US-20170160284-A1 | PROTEIN MELT ANALYSIS USING DIPYRROMETHENEBORON DIFLUORIDE COMPOUNDS | Life Technologies Corporation | 2017-06-08 | — | — | US | disclosed |
| US-9568478-B2 | Protein melt analysis using dipyrrometheneboron difluoride compounds | Life Technologies Corporation (US) | 2017-02-14 | — | — | US | disclosed |
| WO-2011022457-A1 | LACTAM-BASED COMPOUNDS WITH A URETHANE OR UREA FUNCTIONAL GROUP, AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2011-02-24 | — | — | WO | disclosed |
| US-7501413-B2 | Dicarboxamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-03-10 | — | — | US | disclosed |