Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936649 | 0.69 | — | — | |
| SCHEMBL21162599 | 0.68 | LMNA (0.31) | LMNA | |
| SCHEMBL21019700 | 0.67 | MGLL (0.42) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL9734841 | 0.64 | MGLL (0.37) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL19057261 | 0.63 | MGLL (0.46) | MGLLALDH1A1BLMLMNAMAPT | |
| N-Ethylmaleimide SCHEMBL19666 | 0.63 | — | — | |
| SCHEMBL20420335 | 0.63 | — | — | |
| SCHEMBL18594707 | 0.63 | — | — | |
| N-Ethylmaleimide SCHEMBL18209592 | 0.63 | MGLL (1.00) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL12640694 | 0.62 | MGLL (0.44) | MGLLALDH1A1BLMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230232-A1 | SITE-SPECIFIC BIO-CONJUGATION METHODS AND COMPOSITIONS USEFUL FOR NANOPORE SYSTEMS | Roche Sequencing Solutions, Inc. (US) | 2021-07-29 | — | — | US | disclosed |
| US-11001611-B2 | Site-specific bio-conjugation methods and compositions useful for nanopore systems | Roche Sequencing Solutions, Inc. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20190002509-A1 | SITE-SPECIFIC BIO-CONJUGATION METHODS AND COMPOSITIONS USEFUL FOR NANOPORE SYSTEMS | Genia Technologies, Inc. (US) | 2019-01-03 | — | — | US | disclosed |
| US-20180126000-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | ABBVIE INC. (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002509-A1 | SITE-SPECIFIC BIO-CONJUGATION METHODS AND COMPOSITIONS USEFUL FOR NANOPORE SYSTEMS | APEX1, MSN, TIAL1 | MGLL 3297/4885ALDH1A1 4864/4885BLM 376/4885 |
| US-20180126000-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | NR3C1, NR3C2, MC2R | MGLL 2461/4885ALDH1A1 3434/4885BLM 2995/4885 |
| US-20210230232-A1 | SITE-SPECIFIC BIO-CONJUGATION METHODS AND COMPOSITIONS USEFUL FOR NANOPORE SYSTEMS | APEX1, MSN, TIAL1 | MGLL 3297/4885ALDH1A1 4864/4885BLM 376/4885 |
| US-11001611-B2 | Site-specific bio-conjugation methods and compositions useful for nanopore systems | APEX1, MSN, TIAL1 | MGLL 3297/4885ALDH1A1 4864/4885BLM 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.