Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 9/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70577 | 0.85 | HCAR2 (0.59) | TP53ALPLCA12MAPK1HCAR2 | |
| SCHEMBL8068037 | 0.83 | ALPL (0.47) | TP53ALPLCA12MAPK1HCAR2 | |
| Water SCHEMBL1267709 | 0.83 | HCAR2 (0.57) | TP53ALPLCA12MAPK1HCAR2 | |
| Hydrochloric Acid SCHEMBL11595364 | 0.83 | HCAR2 (0.57) | TP53ALPLCA12MAPK1HCAR2 | |
| Hydrochloric Acid SCHEMBL7723258 | 0.83 | HCAR2 (0.57) | TP53ALPLCA12MAPK1HCAR2 | |
| SCHEMBL28638090 | 0.83 | HCAR2 (0.57) | TP53ALPLCA12MAPK1HCAR2 | |
| SCHEMBL19987833 | 0.83 | HCAR2 (0.57) | TP53ALPLCA12MAPK1HCAR2 | |
| Ammonia Solution, Strong SCHEMBL28463590 | 0.81 | HCAR2 (0.55) | TP53ALPLCA12MAPK1HCAR2 | |
| SCHEMBL8068032 | 0.79 | TP53 (0.47) | TP53ALPLCA12MAPK1HCAR2 | |
| SCHEMBL1815487 | 0.79 | MAPK1 (0.48) | TP53ALPLCA12MAPK1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451450-B1 | Inhibitors of proline racemase enzymes for the treatment of Trypanosoma spp infections | PASTEUR INSTITUT (FR) | 2014-07-02 | — | — | EP | disclosed |
| WO-2011004323-A1 | NEW INHIBITORS OF PROLINE RACEMASE ENZYMES | INSTITUT PASTEUR (FR) | 2011-01-13 | — | — | WO | disclosed |