Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK known ✓ | Q06187 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 13/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.52 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.52 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28463590 | 0.98 | HCAR2 (0.55) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL70577 | 0.98 | HCAR2 (0.59) | HCAR2DAOHCAR3CYTH3BTK | |
| Hydrochloric Acid SCHEMBL11595364 | 0.95 | HCAR2 (0.57) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL19987833 | 0.95 | HCAR2 (0.57) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL28638090 | 0.95 | HCAR2 (0.57) | HCAR2DAOHCAR3CYTH3BTK | |
| Hydrochloric Acid SCHEMBL7723258 | 0.95 | HCAR2 (0.57) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL12168148 | 0.83 | HCAR2 (0.59) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL5599765 | 0.83 | HCAR2 (0.53) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL8068032 | 0.83 | TP53 (0.47) | HCAR2DAOHCAR3CYTH3BTK | |
| SCHEMBL12943881 | 0.83 | TP53 (0.47) | HCAR2DAOHCAR3CYTH3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878381-B | Granulated fermentation fertilizer and production process and application thereof | 淮北师范大学 | 2025-01-03 | — | — | CN | claimed |
| CN-119242727-A | Method for producing acrylamide monomer solution | 安徽巨成精细化工有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118345988-B | A-level heat-preservation gypsum board | 杰森新材料有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119092798-A | MOF-based solid electrolyte composite membrane and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2024-12-06 | — | — | CN | claimed |
| CN-119020346-A | Biocatalyst for producing acrylamide by microbiological method and preparation method thereof | 安徽巨成精细化工有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-118930896-A | Method for continuously preparing MOF-303 metal framework material and purification method | 南京工业大学 | 2024-11-12 | — | — | CN | claimed |
| CN-118878381-A | Granulated fermentation fertilizer and production process and application thereof | 淮北师范大学 | 2024-11-01 | — | — | CN | claimed |
| CN-118281245-A | MOF-derived porous nitrogen-doped carbon-supported Pd catalyst and preparation method and application thereof | 安徽理工大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118122280-A | Organic metal framework@graphene oxide composite material and preparation method and application thereof | 海南大学 | 2024-06-04 | — | — | CN | claimed |
| CN-117504832-A | Preparation method of MOF@metal substrate | 广东轻工职业技术学院 | 2024-02-06 | — | — | CN | claimed |
| CN-115449087-A | Preparation method of MOF-303 | 北京化工大学 | 2022-12-09 | — | — | CN | claimed |
| CN-115178107-A | Method for preparing MOF-303/AAO composite membrane through hydrothermal self-growth and application | 成都理工大学 | 2022-10-14 | — | — | CN | claimed |
| US-8802608-B2 | Composition for cleaning and rust prevention and process for producing semiconductor element or display element | Mitsubishi Gas Chemical Comany, Inc. (JP) | 2014-08-12 | — | — | US | claimed |
| US-20100197136-A1 | COMPOSITION FOR CLEANING AND RUST PREVENTION AND PROCESS FOR PRODUCING SEMICONDUCTOR ELEMENT OR DISPLAY ELEMENT | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2010-08-05 | — | — | US | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |