SCHEMBL1294840

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18648483	0.88	ALDH1A1 (0.43)	ALDH1A1GAACYP4F2CYP4A11DRD2
	SCHEMBL1294634	0.82	CA9 (0.39)	CYP19A1CYP11B1CYP11B2BRD4CRBN
	SCHEMBL14562688	0.78	HDAC3 (0.38)	ALDH1A1GAABRD4CRBNMAOA
	SCHEMBL11770569	0.75	MAOA (0.47)	ALDH1A1DRD2MAPTMAPK1KDM4E
	SCHEMBL10646898	0.74	ALDH1A1 (0.54)	ALDH1A1GAACYP4F2CYP4A11DRD2
	SCHEMBL15828392	0.74	CYP4F2 (0.41)	ALDH1A1GAACYP4F2CYP4A11MAPT
	SCHEMBL14641744	0.74	CA9 (0.39)	DRD2CYP19A1CYP11B1CYP11B2BRD4
	SCHEMBL12110597	0.74	NQO2 (0.43)	ALDH1A1DRD2BRD4CRBN
	SCHEMBL12110181	0.74	ALDH1A1 (0.35)	ALDH1A1GAACYP4F2CYP4A11DRD2
	SCHEMBL1294737	0.73	MAOA (0.33)	BRD4CRBNMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.