SCHEMBL1294634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14562688	0.84	HDAC3 (0.38)	CA9HDAC3HDAC4HDAC1HDAC2
	SCHEMBL18648565	0.83	NPSR1 (0.56)	CA9HDAC3HDAC4HDAC1HDAC2
	SCHEMBL1294840	0.82	ALDH1A1 (0.42)	HDAC3HDAC4HDAC1HDAC2HDAC8
	SCHEMBL14641744	0.80	CA9 (0.39)	CA9MAOAMAOBCYP19A1CYP11B1
	SCHEMBL1294737	0.79	MAOA (0.33)	CA9MAOAMAOBBRD4CRBN
	SCHEMBL1294298	0.75	MAOB (0.50)	CA9MAOAMAOBNPC1MAPK13
	SCHEMBL11767335	0.75	MAOA (0.50)	HDAC3HDAC4HDAC1HDAC2HDAC8
	SCHEMBL23576507	0.75	RXRG (0.43)	NPSR1POLB
	SCHEMBL30043060	0.75	RXRG (0.43)	NPSR1POLB
	SCHEMBL12110597	0.75	NQO2 (0.43)	NPSR1BRD4CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.