Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988181 | 0.91 | VCP (0.38) | KDM4EALDH1A1RAB9ANPC1TDP1 | |
| SCHEMBL12584924 | 0.88 | RAB9A (0.41) | KDM4EALDH1A1RAB9ANPC1DRD2 | |
| SCHEMBL988182 | 0.88 | HTR4 (0.35) | KDM4EALDH1A1RAB9ANPC1TDP1 | |
| SCHEMBL987404 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1RAB9ANPC1DRD2 | |
| SCHEMBL12584914 | 0.79 | HTR2B (0.43) | KDM4EALDH1A1L3MBTL1DRD2DRD4 | |
| SCHEMBL987689 | 0.78 | PTGER4 (0.40) | KDM4EALDH1A1RAB9ANPC1DRD2 | |
| SCHEMBL12584603 | 0.78 | DRD2 (0.40) | KDM4EALDH1A1RAB9ANPC1L3MBTL1 | |
| SCHEMBL12948849 | 0.78 | RAB9A (0.44) | KDM4EALDH1A1RAB9ANPC1DRD2 | |
| Bicarbonate SCHEMBL16143667 | 0.77 | NPC1 (0.43) | KDM4EALDH1A1RAB9ANPC1CNR1 | |
| SCHEMBL987406 | 0.77 | KDM4E (0.36) | KDM4EALDH1A1RAB9ANPC1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277858-A1 | AMIDE COMPOUND | Astellas Pharma Inc. (JP) | 2011-01-26 | — | — | EP | disclosed |