Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 4/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12951909 | 0.85 | MAPT (0.52) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10592159 | 0.78 | CCR2 (0.52) | CCR2GPR35FABP4NOTUMFABP3 | |
| SCHEMBL12951911 | 0.77 | ALDH1A1 (0.42) | MEN1HPGDKMT2AGSK3AGSK3B | |
| SCHEMBL14229126 | 0.71 | CCR2 (0.58) | CCR2GPR35NOTUMTSHRPOLB | |
| SCHEMBL289221 | 0.70 | CAPN1 (0.54) | CCR2GPR35FABP4NOTUMTSHR | |
| SCHEMBL3802542 | 0.70 | ALDH1A1 (0.62) | CCR2GPR35NOTUMMEN1HPGD | |
| SCHEMBL12584599 | 0.69 | CCR2 (0.53) | CCR2FABP4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5378162 | 0.68 | CCR2 (1.00) | CCR2GPR35POLBALDH1A1 | |
| SCHEMBL12951913 | 0.68 | F2 (0.44) | NOTUMPOLBRECQLMEN1HPGD | |
| SCHEMBL7052102 | 0.66 | CCR2 (0.56) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |