SCHEMBL12952583

SCHEMBL12952583

CO[C@@H]1C(C(=O)O)O[C@@H](OC2C(NC(C)=O)[C@H](C)OC(CO)[C@H]2O)C(O)C1O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.44
▸ LGALS3 P17931 6/20 0.44
▸ LGALS8 O00214 2/20 0.44
▸ LGALS4 P56470 1/20 0.44
▸ MDK P21741 3/20 0.43
▸ BDNF P23560 3/20 0.43
▸ PTN P21246 2/20 0.43
▸ CD69 Q07108 1/20 0.41
▸ LGALS1 P09382 1/20 0.41
▸ LGALS7; LGALS7B P47929 1/20 0.41
▸ LGALS9 O00182 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ F10 P00742 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15274904 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL12213976 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15215584 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL18254178 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL12085239 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL25121361 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15082697 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL4544701 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL21374694 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL10157433 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216575-A1 BIOPOLYMER SCAFFOLDS AND METHODS FOR PRODUCTION OR USE THEREOF BIONOVA MEDICAL, INC. (US) 2024-07-04 — — US disclosed
US-20230270761-A1 IMMUNOMODULATORY, ORAL MICROBIOME ALTERING AND TISSUE REGENERATIVE ORAL CARE COMPOSITIONS AND METHODS OF USE IN THE PREVENTION AND TREATMENT OF PERIODONTAL AND PERI-IMPLANT DISEASES JANOSI FAIR KATALIN (US) 2023-08-31 — — US disclosed
US-20230226200-A1 CANNABINOID-HYALURONIC ACID BIOCONJUGATES LONDON PHARMACEUTICALS AND RESEARCH CORPORATION (CA) 2023-07-20 — — US disclosed
EP-1951761-B1 NEW DERIVATIVES OF HYALURONIC ACID, THEIR PREPARATION PROCESS AND THEIR USES CENTRE NAT RECH SCIENT (FR) 2011-01-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270761-A1 IMMUNOMODULATORY, ORAL MICROBIOME ALTERING AND TISSUE REGENERATIVE ORAL CARE COMPOSITIONS AND METHODS OF USE IN THE PREVENTION AND TREATMENT OF PERIODONTAL AND PERI-IMPLANT DISEASES AHCY, CD44, TIMCC MAPK1 2827/4885LGALS3 605/4885LGALS8 2027/4885
US-20230226200-A1 CANNABINOID-HYALURONIC ACID BIOCONJUGATES CNR2, CNR1, FAAH MAPK1 2199/4885LGALS3 1341/4885LGALS8 2263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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