SCHEMBL10157433

SCHEMBL10157433

CO[C@@H]1C(C(=O)O)O[C@@H](OC2[C@H](O)C(CO)OC(C)[C@H]2NC(C)=O)[C@@H](O)C1O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.44
▸ LGALS3 P17931 6/20 0.44
▸ LGALS8 O00214 2/20 0.44
▸ LGALS4 P56470 1/20 0.44
▸ MDK P21741 3/20 0.43
▸ BDNF P23560 3/20 0.43
▸ PTN P21246 2/20 0.43
▸ CD69 Q07108 1/20 0.41
▸ LGALS1 P09382 1/20 0.41
▸ LGALS7; LGALS7B P47929 1/20 0.41
▸ LGALS9 O00182 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ F10 P00742 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12952583 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15274904 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL12213976 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15215584 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL18254178 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL12085239 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL25121361 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL15082697 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL4544701 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK
SCHEMBL21374694 1.00 MAPK1 (0.44) MAPK1LGALS3LGALS8LGALS4MDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321420-A1 MICRONEEDLE ARRAY WITH ACTIVE INGREDIENT ALLERGAN, INC. (US) 2023-10-12 — — US disclosed
US-20170202982-A1 Hyaluronic Acid-Based Nanoparticles as Biosensors for Imaging-Guided Surgery and Drug Delivery Vehicles and Methods Associated Therewith WAKE FOREST UNIVERSITY 2017-07-20 — — US disclosed
US-9662350-B2 Pharmaceutical composition and method for inhibiting inflammation CHINA MEDICAL UNIVERSITY (TW) 2017-05-30 — — US disclosed
US-9549987-B2 Glucose responsive hydrogel comprising PBA-grafted hyaluronic acid (HA) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2017-01-24 — — US disclosed
US-20160096904-A1 SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND PROCESSES FOR MAKING THE SAME AKZO NOBEL CHEMICALS INT BV (NL) 2016-04-07 — — US disclosed
US-9180161-B2 CAR peptide for homing, diagnosis and targeted therapy for pulmonary and fibrotic disorders Sanford Burnham Prebys Medical Discovery Institute (US) 2015-11-10 — — US disclosed
US-20150283247-A1 GLUCOSE RESPONSIVE HYDROGEL COMPRISING PBA-GRAFTED HYALURONIC ACID (HA) CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2015-10-08 — — US disclosed
US-20150094279-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING INFLAMMATION CHINA MEDICAL UNIVERSITY (TW) 2015-04-02 — — US disclosed
US-20140274867-A1 CLEANSING BARS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS AND METHODS OF USE THEREOF JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2014-09-18 — — US disclosed
US-20130196896-A1 CAR PEPTIDE FOR HOMING, DIAGNOSIS & TARGETED THERAPY FOR PULMONARY AND FIBROTIC DISORDERS SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-08-01 — — US disclosed
US-20120034164-A1 TRUNCATED CAR PEPTIDES AND METHODS AND COMPOSITIONS USING TRUNCATED CAR PEPTIDES Sanford-Burnham Medical Research Institute California 2012-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170202982-A1 Hyaluronic Acid-Based Nanoparticles as Biosensors for Imaging-Guided Surgery and Drug Delivery Vehicles and Methods Associated Therewith CD44, HLA-A, HLA-C MAPK1 2043/4885LGALS3 15/4885LGALS8 24/4885
US-20150283247-A1 GLUCOSE RESPONSIVE HYDROGEL COMPRISING PBA-GRAFTED HYALURONIC ACID (HA) CD44, PGD, SLC2A9 MAPK1 281/4885LGALS3 337/4885LGALS8 905/4885
US-20230321420-A1 MICRONEEDLE ARRAY WITH ACTIVE INGREDIENT CUTA, KRT18, MMP17 MAPK1 1382/4885LGALS3 1959/4885LGALS8 682/4885
US-20150094279-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR INHIBITING INFLAMMATION CD44, IL17A, PROC MAPK1 3472/4885LGALS3 311/4885LGALS8 416/4885
US-20120034164-A1 TRUNCATED CAR PEPTIDES AND METHODS AND COMPOSITIONS USING TRUNCATED CAR PEPTIDES LNPEP, CD47, CARS1 MAPK1 4124/4885LGALS3 263/4885LGALS8 304/4885
US-20130196896-A1 CAR PEPTIDE FOR HOMING, DIAGNOSIS & TARGETED THERAPY FOR PULMONARY AND FIBROTIC DISORDERS CXCL12, CCL2, CCR9 MAPK1 2838/4885LGALS3 308/4885LGALS8 621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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